Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection
Recruiting · NCT07462091 · Interventional (participants receive a specific treatment) · Lead sponsor: Northern Jiangsu People's Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection
What this trial is about
This study aimed to evaluate the effectiveness and safety of vagus nerve-guided laparoscopic splenectomy and azygoportal disconnection, and to assess its impact on postoperative digestive complications and quality of life.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
- Splenomegaly with secondary hypersplenism
- Bleeding portal hypertension
- No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT
- Informed consent to participate in the study
Exclusion criteria
- Delayed gastric emptying
- Diarrhea
- Hepatocellular carcinoma or any other malignancy,
- Hypercoagulable state other than the liver disease related
- DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs.
- Child - Pugh C
- Recent peptic ulcer disease
- History of Hemorrhagic stroke
- Pregnancy.
- Uncontrolled Hypertension
- Human immunodeficiency virus (HIV) infection
Where it is running
2 locations listed.
- Clinical Medical College of Yangzhou University - Yangzhou, Jiangsu, China
- Clinical Medical College, Yangzhou University - Yangzhou, Jiangsu, China