Brief Title: Aerobic Training on Cerebrovascular Function, Cognition and Gait in Parkinson's Disease
Recruiting · NCT07478146 · Interventional (participants receive a specific treatment) · Lead sponsor: Raphael Mendes Ritti Dias
View the official record on ClinicalTrials.gov →Interventions studied
Aerobic trainingUsual Care
What this trial is about
This randomized controlled trial will investigate the effects of a 12-week supervised aerobic training program on cerebrovascular function, peripheral vascular health, cardiovascular autonomic modulation, cognition, non-motor symptoms, sleep, mood, gait biomechanics, quality of life, and body composition in patients with Parkinson's disease (Hoehn \& Yahr stages 1-3). Participants will be randomly allocated to aerobic training or usual care.
Who can take part
Age range
40 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Clinical diagnosis of Parkinson's disease
- Hoehn \& Yahr stages 1-3
- Stable antiparkinsonian medication for at least 4 weeks
- Montreal Cognitive Assessment (MoCA) score ≥ 18
- Ability to walk independently (with or without assistive device)
- Medical clearance for participation in moderate-intensity exercise
Exclusion criteria
- Change in medication
- Contraindication to exercise
Where it is running
1 location listed.
- Associação Brasil Parkinson - São Paulo, São Paulo, Brazil