Efficacy of L-menthol on Breathlessness in Asthma
Recruiting · NCT07500974 · Interventional (participants receive a specific treatment) · Lead sponsor: Region Skane
View the official record on ClinicalTrials.gov →Interventions studied
L-mentholPlacebo
What this trial is about
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- the subject has given written consent to participate in the study
- physician diagnosis of Asthma according to international guidelines
- mMRC (modified Medical Research Council) score of 1 or above
- age 18 years or older
- able to cycle
- able to understand and talk Swedish to participate in the study procedures, as judged by the Investigators.
Exclusion criteria
- resting peripheral oxygen saturation (SpO2) \< 92%
- hospitalization or clinical instability during the last four weeks
- treatment with supplementary oxygen at rest or during exercise
- contraindication to exercise testing in accordance with clinical practice guidelines
- expected survival shorter than six months as judged by the Investigator
- medical conditions including congestive heart failure, acute coronary artery disease, neuromuscular diseases, severe psychiatric illness, and olfaction disorder.
Where it is running
2 locations listed.
- Lund University hospital and Region Skåne - Lund, Sweden
- Blekinge Institute of Technology - Karlskrona, Blekinge County, Sweden