Implementing Low-dose ct Lung Cancer Screening in France.

Recruiting · NCT07513818 · Interventional (participants receive a specific treatment) · Lead sponsor: Assistance Publique - Hôpitaux de Paris

Interventions studied

Low-dose computed tomography of the chest

The main objective is to estimate the detection rate of lung cancer in the population screened by low-dose chest CT scans.

Age range

50 Years to 74 Years

Sex

All (male and female)

Healthy volunteers

No - a diagnosis or condition is required

Phase

Not applicable (e.g. observational or device study)

Study type

Interventional (participants receive a specific treatment)

Adults aged 50-74 years
Active or former smoker having quit less than 15 years ago
Smoking history of at least 20 pack-years, or 15 cigarettes/day for 25 years or 10 cigarettes/day for 30 years
Affiliation with a social security scheme
Written informed consent prior to study participation
Temporary

Chest CT scan performed within the previous 12 months
Signs of respiratory infection (fever, productive cough)
Exclusion Criteria:
Severe co-morbidities contraindicating exploration and/or management (including stereotactic surgery or radiotherapy) of lung cancers
Poor general status (PS2 and above)
Rest dyspnea (mMRC4)
Cancer under active surveillance by thoracic computed tomography (CT pr PET-CT)
Personal history of lung cancer
Symptoms raising suspicion of lung cancer (hemoptysis, unexplained weight loss, recent onset or modification of respiratory symptoms,…)

2 locations listed.