Eccentric Muscle Training in Cardiac Rehabilitation
Recruiting · NCT07636343 · Interventional (participants receive a specific treatment) · Lead sponsor: University Hospital, Antwerp
View the official record on ClinicalTrials.gov →Interventions studied
aerobic bike trainingaerobic treadmill trainingeccentric bike trainingeccentric overload trainingtraditional dynamic strength training
What this trial is about
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used. Researchers will compare a training program of eccentric overload training and eccentric cycling training with a traditional training program of strength and cardio training in people with heart failure with reduced ejection fraction. This study will be delivered in a cardiac rehabilitation setting.
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- HFrEF patients with ejection fraction \<40%
- Exercise intolerance (\<85% of predicted VO2 peak)
- clinically stable for \> 6 weeks, optimal medical treatment for \> 6 weeks
Exclusion criteria
- Contra indications for cardiac exercise rehabilitation as per consensus guidelines and recommendations
- Musculoskeletal disorders that hamper (progression in) strength training
- Non-stabilized acute coronary syndrome
- Current acute heart failure (decompensation)
- Patient having sustained a recent (\<3 months) procedure that could act as a confounder to increase VO2peak (i.e., coronary artery bypass graft surgery, percutaneous coronary intervention, cardiac resynchronization therapy, valve surgery or reparation)
Where it is running
1 location listed.
- UHAntwerp - Edegem, Belgium