A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Recruiting · NCT07639021 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The purpose of the study is to find out if NNC0662-0419 is safe and effective for treating participants living with obesity.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 2
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Male or female (sex assigned at birth, inclusive of all gender identities).
- Age 18 years or above at the time of signing the informed consent.
- Body mass index (BMI) greater than or equal to (≥) 30.0 kilogram per square meter (kg/m\^2) at screening.
- Participant must have a desire and be committed to lose at least 25 percentage (%) of their body weight from randomisation.
Exclusion criteria
- Known or suspected hypersensitivity to study intervention(s) or related products.
- Treatment with any medication prescribed for the indication of obesity or weight management (e.g. glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1/gastric inhibitory peptide (GIP) RAs (or any other GLP-1 based treatment) or amylin analogues)) within 90 days before screening.
- Glycated haemoglobin (HbA1c) ≥ 6.5% (48 Millimoles per mole \[mmol/mol\]) as measured by the central laboratory at screening.
- History of type 1 or type 2 diabetes mellitus.
Where it is running
25 locations listed across 17 US states.
- Chambliss Clinical Trials, LLC - Montgomery, Alabama, United States
- FDRC - Costa Mesa, California, United States
- Los Angeles Institute for Metabolic Research - Los Angeles, California, United States
- Encore Medical Research LLC - Hollywood, Florida, United States
- South Broward Research LLC - Miramar, Florida, United States
- West Orange Endocrinology - Ocoee, Florida, United States
- Cedar-Crosse Research Center - Chicago, Illinois, United States
- Great Lakes Clinical Trials - Chicago, Illinois, United States
- Midwest Inst For Clin Res - Indianapolis, Indiana, United States
- L-MARC Research Center - Louisville, Kentucky, United States
- Endo And Metab Cons - Rockville, Maryland, United States
- StudyMetrix Research LLC - City of Saint Peters, Missouri, United States
- Great Lakes Medical Research - Westfield, New York, United States
- KDCILM, LLC & Accellacare US, Inc. - Wilmington, North Carolina, United States
- Family Practice Center of Wadsworth Inc. - Wadsworth, Ohio, United States
- UPA Ctr Weight and Eating Dis - Philadelphia, Pennsylvania, United States
- Clinical Res Collaborative - Cumberland, Rhode Island, United States
- Holston Medical Group_Bristol - Bristol, Tennessee, United States
- Holston Medical Group - Kingsport, Tennessee, United States
- Clinical Research Associates - Nashville, Tennessee, United States
- PlanIt Research, PLLC - Houston, Texas, United States
- Pinnacle Clinical Research - San Antonio, Texas, United States
- National Clin Res Inc. - Richmond, Virginia, United States
- Rainier Clin Res Ctr Inc - Renton, Washington, United States
- Isis Clinical Res. Ctr P.S.C. - Guaynabo, Puerto Rico