Genetic, Microbiological and Behavioral Factors in Obesity
Recruiting · NCT07650149 · Observational (researchers observe without assigning treatment) · Lead sponsor: Jan Kochanowski University
View the official record on ClinicalTrials.gov →Interventions studied
genetic polymorphismgut microbiome
What this trial is about
This study will assess the impact of genetic markers, microbiological (microbiome) and behavioral factors on tolerance, adherence and effectiveness of dual GLP1/GIP RA in the treatment of obesity. 200 consecutive patients who meet all inclusion and none of the exclusion criteria will be enrolled.
Who can take part
Age range
18 Years to 60 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age 18-60 years
- Consent to participate in the study and providing informed written consent
- Overweight or obese with a BMI \>27
Exclusion criteria
- Contraindications to tirzepatide use:
- Type 1 or type 2 diabetes
- Pregnancy or breastfeeding
- Cancer
- Heart failure
- Expected lack of patient compliance
- Taking immunosuppressive medications, steroids, NSAIDs, antibiotics (within 2 weeks prior to sample collection),
- Autoimmune and inflammatory diseases, acute infectious diseases, AIDS, tuberculosis
- Mental illness
- Alcohol dependence syndrome
- Liver cirrhosis
- Post-myocardial infarction or stroke
Where it is running
2 locations listed.
- Waga Zmiany - Krakow, Poland
- Luxmed sp zoo - Warsaw, Poland