Chronology and Sequence of Premonitory Symptoms
Recruiting · NCT07681466 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of Roma La Sapienza
View the official record on ClinicalTrials.gov →What this trial is about
The purpose of this study is to prospectively investigate the temporal sequence of premonitory symptoms across multiple migraine attacks.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Diagnosis of episodic (EM) or chronic migraine (CM) or CM with medication overuse headache (MOH) according to ICHD-III criteria;
- Age between 18 and 65 years;
- At least 2 migraine days (MMD) in the month preceding the inclusion;
- Migraine history of at least 12 months prior to inclusion
- Signed written informed consent.
Exclusion criteria
- History or current diagnosis of secondary headache disorders as defined by ICHD-III;
- History of other neurological comorbidities or major psychiatric disorders;
- History of migraine for \< 12 months prior to the inclusion;
- Opioid overuse according to the ICHD-III criteria;
- Pregnancy or breastfeeding.
Where it is running
1 location listed.
- Sapienza University of Rome, Polo Pontino, centro cefalee, ICOT - Latina, Italy, Italy