Evaluation of the Accuracy of Immunostaining of Claudin 2 to Detect Active or Inactive Inflammation in Endoscopic Biopsies of IBD
Recruiting · NCT07710287 · Observational (researchers observe without assigning treatment) · Lead sponsor: IRCCS Policlinico S. Donato
View the official record on ClinicalTrials.gov →What this trial is about
In view of the increasing evidence of the importance of mucosal healing as a combination of endoscopic and histologic healing, and the complexity and lack of complete agreement of the evaluation of histologic healing in IBD, the aim of this study will be to evaluate the accuracy of a new methodology, the immunostaining for Claudine 2 as compared to others standard well-accepted scoring for histologic activity in IBD. The aim is compare the accuracy of this methodology and in addition the correlation with outcomes (i.e. relapse, hospitalization, surgery).
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Confirmed diagnosis of IBD
Exclusion criteria
- Unconfirmed diagnosis of IBD
Where it is running
2 locations listed.
- Gastroenterology IRCCS San Donato Policlinic - San Donato Milanese, Mi, Italy
- Gastroenterology IRCCS San Donato Policlinic - San Donato Milanese, Mi, Italy