Biomarkers for Endometriosis
Recruiting · NCT07713797 · Observational (researchers observe without assigning treatment) · Lead sponsor: Trio Fertility
View the official record on ClinicalTrials.gov →Interventions studied
BCL-6 ProteinSNCG Protein
What this trial is about
Endometriosis is a condition in which tissue similar to the lining of the uterus grows outside the uterus, often causing pain and infertility. Currently, endometriosis can only be definitively diagnosed through invasive procedures like laparoscopy and biopsy. The purpose of this study is to investigate whether the proteins Synuclein Gamma (SNCG) and B-Cell Lymphoma 6 (BCL6), measurable in blood and menstrual fluid, can serve as non-invasive biomarkers to diagnose or monitor endometriosis.
Who can take part
Age range
18 Years to 45 Years
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- for Endometriosis Group:
- Women of reproductive age group (18Y-45Y).
- Women with active endometriosis diagnosed by ultrasound/MRI/laparoscopy.
Exclusion criteria
- for Endometriosis Group:
- Women \<18Y and \>45Y.
- Women with endometriosis during stimulation with gonadotropins.
- Current or prior history of uterine, ovarian, colon, pancreatic, breast or any other type of cancer.
- Any prior history of chronic illness.
- Pregnant women.
- Inclusion Criteria for Control Group:
- Women of reproductive age group (18Y-45Y).
- Women without endometriosis and any other gynaecological problem.
- Exclusion Criteria for Endometriosis Group:
- Women \<18Y and \>45Y
- Prior history of any disease including cancer or chronic illness.
- Pregnant women.
Where it is running
1 location listed.
- Trio Fertility - Toronto, Ontario, Canada