Acupoint Application for Chemotherapy-Induced Nausea and Vomiting in Lung Cancer
Recruiting · NCT07768124 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
5-HT3 receptor antagonist (e.g., ondansetron)Acupoint application
What this trial is about
This single-center, randomized, controlled study evaluates whether acupoint application added to standard 5-HT3 receptor antagonist anti-nausea medication improves control of chemotherapy-induced nausea and vomiting in adults with lung cancer receiving first-line platinum-based chemotherapy. Participants will be randomly assigned to receive either acupoint application plus a 5-HT3 receptor antagonist or the 5-HT3 receptor antagonist alone for one chemotherapy cycle. The study will compare complete control of delayed nausea and vomiting between the two groups.
Who can take part
Age range
18 Years to 75 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Pathologically or cytologically confirmed lung cancer.
- Scheduled to receive first-line platinum-based chemotherapy.
- Aged 18 to 75 years.
- Karnofsky Performance Status (KPS) score ≥ 60.
- Expected survival ≥ 3 months.
- Voluntarily signed written informed consent.
Exclusion criteria
- Known allergy to any component of the acupoint plaster.
- Severe skin disease, infection, or breakdown at the planned acupoint sites. --Pregnant or lactating women.
- Cognitive impairment or psychiatric disorder that prevents completion of study assessments.
- Participation in another interventional clinical trial within 30 days prior to enrollment.
Where it is running
1 location listed.
- The Affiliated Yongchuan Hospital of Chongqing Medical University - Chongqing, Chongqing Municipality, China