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A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER)
NCT04333706 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· California: Los Angeles
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A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
NCT05948865 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Newport Beach, Santa Monica
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A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
NCT05970497 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Rancho Santa Margarita
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A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
NCT06440005 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
NCT06682793 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles
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A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
NCT06051695 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Los Angeles, Stanford
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ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
NCT03686124 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Stanford
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Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
NCT02253251 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
NCT05181826 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Redondo Beach
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Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer
NCT05297734 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, Fresno, Fruitdale, Fullerton
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FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT05919264 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto, San Francisco, Santa Monica
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GOLD: Brief Intervention to Reduce Anxiety and Promote Resilience in Families of Youth With Cancer
NCT05415007 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 8 Years to 18 Years ·
Sex: All (male and female)
· California: San Francisco
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Phase I Human Analytics (HALO) Study
NCT05423860 ·
Phase: Not specified ·
Ages: 45 Years to 90 Years ·
Sex: Male
· California: Indian Wells
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SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
NCT03452774 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· California: Duarte, Irvine, La Jolla, Orange
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Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
NCT04981119 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Duarte, La Jolla, Palo Alto, Santa Monica
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Statins to Prevent Cancer Associated Blood Clots
NCT07303816 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Irvine
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TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
NCT04485013 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles, Newport Beach
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The STOP-MED CTRCD Trial
NCT06183437 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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eMOTION: Examining Affective Mechanisms in Physical Activity Engagement
NCT06570642 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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eMOTION: Examining Implicit Attitudes in Physical Activity Engagement
NCT07044570 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles