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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Canoga Park, Concord, Fremont
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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Concord, Sacramento, Victorville
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A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Dimas, San Ramon
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A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
NCT07268638 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Chula Vista, Los Angeles, San Dimas
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A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
NCT06933472 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· California: Granada Hills, San Dimas
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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
NCT06749457 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· California: Chula Vista, Glendale, Granada Hills, Los Angeles
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A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
NCT06712654 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Chula Vista, Los Angeles, San Dimas
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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
NCT07107945 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· California: Palo Alto, Sacramento, San Francisco
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A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
NCT07753993 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Chula Vista, Concord, Daly City, Fremont
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A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
NCT07024823 ·
Phase: Phase 1 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Glendale
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A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
NCT05457283 ·
Phase: Phase 3 ·
Ages: 1 Year to 18 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto, San Diego
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A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
NCT03633708 ·
Phase: Phase 3 ·
Ages: 0 Years to 18 Years ·
Sex: All (male and female)
· California: Los Angeles
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Achieving Chronic Care equiTy by leVeraging the Telehealth Ecosystem
NCT06598436 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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Adding Urea to the Final Dialysis Fluid
NCT06366230 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant
NCT05106387 ·
Phase: Not specified ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: Los Angeles, Orange, San Francisco
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CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
NCT05931276 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Long Beach
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CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
NCT05422534 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Sacramento
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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· California: Arroyo Grande, Bakersfield, Burbank, Carmichael
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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
NCT05485961 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Bakersfield, Beverly Hills, Chula Vista, Fresno
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Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
NCT05880537 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Sylmar, Torrance
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Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
NCT05525507 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors
NCT03803423 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Diego
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EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
NCT06531824 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Beverly Hills, Sylmar, West Hills
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Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy
NCT06712407 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fresno, Orange, San Bernardino, San Francisco
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Ferric Citrate and Chronic Kidney Disease in Children
NCT04741646 ·
Phase: Phase 2 ·
Ages: 6 Years to 18 Years ·
Sex: All (male and female)
· California: Los Angeles, Orange, San Francisco
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Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
NCT05465044 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Long Beach, West Los Angeles
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Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants
NCT06613568 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: San Dimas
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Pivotal Study of the Velocity™ pAVF System
NCT07153939 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Concord, Riverside
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Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
NCT06516653 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Long Beach
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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
NCT04634916 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, San Francisco
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Preoperative Hemodialysis Timing in Patients With End-Stage Kidney Disease: The POD-ESKD Pilot Trial
NCT07339202 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Stanford
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Renal Impairment Study for Oral EC5026
NCT07694544 ·
Phase: Phase 1 ·
Ages: 55 Years and older ·
Sex: All (male and female)
· California: Sacramento
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Repletion of Ergothioneine in Patients With Kidney Failure
NCT06487546 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
NCT06001827 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Garden Grove
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SPYRAL GEMINI Pilot Study
NCT06907147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Stanford
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Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD
NCT04580420 ·
Phase: Phase 2 ·
Ages: No age limits stated ·
Sex: All (male and female)
· California: San Francisco
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Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
NCT07059962 ·
Phase: Not specified ·
Ages: 21 Years and older ·
Sex: All (male and female)
· California: Victorville
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Sit Less, Interact and Move More (SLIMM) 2 Study
NCT05173714 ·
Phase: Phase 2 ·
Ages: 20 Years and older ·
Sex: All (male and female)
· California: Stanford
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Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
NCT04984226 ·
Phase: Phase 2 ·
Ages: 21 Years to 85 Years ·
Sex: All (male and female)
· California: Sacramento
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Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Stanford
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Staged Kidney Transplantation During Combined Heart/Kidney Transplantation
NCT06877169 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma
NCT05287945 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Orange, Palo Alto, San Francisco
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Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
NCT07271186 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Huntington Beach, Northridge, Oxnard, Salinas
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Transformative Research in Diabetic Nephropathy
NCT02986984 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto