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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Braintree, New Bedford, Worcester
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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Braintree, New Bedford, Worcester
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A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
NCT07268638 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Worcester
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A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
NCT04671771 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
NCT07753993 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, New Bedford
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A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
NCT05457283 ·
Phase: Phase 3 ·
Ages: 1 Year to 18 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
NCT04500665 ·
Phase: Phase 2 ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
NCT05931276 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Care Transitions App for Patients With Multiple Chronic Conditions
NCT06051058 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Jamaica Plain
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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
NCT05485961 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy
NCT07426484 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Direct to Patient Minimal Risk Biospecimen and Data Collection Research
NCT07128966 ·
Phase: Not specified ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Massachusetts: Lexington
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Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1)
NCT07211035 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy
NCT06712407 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Home Hospital for Suddenly Ill Adults
NCT03524222 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Improving Coronary Vascular Health in Women
NCT06843902 ·
Phase: Phase 2 ·
Ages: 45 Years to 75 Years ·
Sex: Female
· Massachusetts: Boston
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Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
NCT05465044 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Incremental Hemodialysis: The TwoPlus Trial
NCT05828823 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis
NCT04399941 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Kidney Precision Medicine Project
NCT04334707 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
NCT06190717 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 84 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Partners Calciphylaxis Biobank
NCT03032835 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
NCT06516653 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
NCT04634916 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Springfield, West Springfield, Worcester
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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
NCT06001827 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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SAfety of Regional Citrate Anticoagulation (SARCA Study)
NCT05339139 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Worcester
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SPYRAL GEMINI Pilot Study
NCT06907147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD
NCT04580420 ·
Phase: Phase 2 ·
Ages: No age limits stated ·
Sex: All (male and female)
· Massachusetts: Boston
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Safety and Efficacy of Empagliflozin in Hemodialysis
NCT05786443 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Shingrix in Renal Transplant Recipients
NCT04128189 ·
Phase: Phase 3 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Symptom Monitoring With Supported Feedback in Advanced Chronic Kidney Disease
NCT07186218 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Symptom Monitoring in Hemodialysis
NCT05738330 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Waltham
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The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease
NCT07222683 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston