-
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
NCT06830629 ·
Phase: Phase 2 ·
Ages: 18 Years to 68 Years ·
Sex: All (male and female)
· North Carolina: Durham, Fayetteville, Greensboro, Shelby
-
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Greenville, Hickory, Jacksonville, Kinston
-
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Kinston, Raleigh, Winston-Salem
-
A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
NCT07222917 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Greenville, Jacksonville, New Bern
-
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Morehead City, Winston-Salem
-
A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
NCT07268638 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: New Bern
-
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
NCT06749457 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· North Carolina: Kinston, Winston-Salem
-
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
NCT04671771 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· North Carolina: Charlotte, Durham, Raleigh
-
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
NCT07753993 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Greensboro, Morehead City, Rocky Mount, Shelby
-
Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center
NCT01016613 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· North Carolina: Charlotte
-
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· North Carolina: Asheville, Cary, Clinton, Clyde
-
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
NCT05485961 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte, Durham, Greenville, Kinston
-
CommunityRx-Kidney Health
NCT07237295 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Beulaville
-
Duke APOL1 Research Biorepository
NCT04160507 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Durham
-
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
NCT06531824 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte, Greensboro, Winston-Salem
-
Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy
NCT06712407 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Raleigh
-
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
NCT06738394 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years to 100 Years ·
Sex: All (male and female)
· North Carolina: Winston-Salem
-
Ferric Citrate and Chronic Kidney Disease in Children
NCT04741646 ·
Phase: Phase 2 ·
Ages: 6 Years to 18 Years ·
Sex: All (male and female)
· North Carolina: Durham
-
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
NCT06906640 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Durham
-
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
NCT06906627 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Durham, Houston
-
Incremental Hemodialysis: The TwoPlus Trial
NCT05828823 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill, Winston-Salem
-
Kidney Precision Medicine Project
NCT04334707 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill
-
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
NCT06190717 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 84 Years ·
Sex: All (male and female)
· North Carolina: Concord
-
PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis
NCT06422871 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Raleigh
-
Pivotal Study of the Velocity™ pAVF System
NCT07153939 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· North Carolina: Charlotte
-
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
NCT04634916 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Raleigh
-
RaDIANT Health Systems Intervention
NCT07033117 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· North Carolina: Durham
-
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
NCT06001827 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte, Raleigh
-
SPYRAL GEMINI Pilot Study
NCT06907147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· North Carolina: Chapel Hill
-
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
NCT07271186 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· North Carolina: Greenville, New Bern, Winston-Salem
-
Transformative Research in Diabetic Nephropathy
NCT02986984 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· North Carolina: Chapel Hill
-
Transforming Hemodialysis-Related Vascular Access Education
NCT05997875 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill