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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
NCT06830629 ·
Phase: Phase 2 ·
Ages: 18 Years to 68 Years ·
Sex: All (male and female)
· Tennessee: Chattanooga
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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga, Knoxville, Nashville
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A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
NCT07268638 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga
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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
NCT06749457 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Tennessee: Knoxville
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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
NCT07107945 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· Tennessee: Nashville
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A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
NCT07753993 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville, Morristown
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CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
NCT05422534 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Tennessee: Nashville
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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· Tennessee: Germantown
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Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
NCT05485961 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga, Knoxville, Memphis, Nashville
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Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage
NCT07385651 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
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EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
NCT06531824 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Memphis
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Empagliflozin Treatment in Kidney Transplant Recipients
NCT06013865 ·
Phase: Phase 4 ·
Ages: 19 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
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Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
NCT05465044 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Memphis
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Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
NCT06190717 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 84 Years ·
Sex: All (male and female)
· Tennessee: Chattanooga, Memphis
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Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants
NCT06613568 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Tennessee: Knoxville
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Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.
NCT06858319 ·
Phase: Phase 3 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Tennessee: Brentwood
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Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville, Memphis
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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
NCT04634916 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga, Memphis
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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
NCT06001827 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Memphis
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Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
NCT04984226 ·
Phase: Phase 2 ·
Ages: 21 Years to 85 Years ·
Sex: All (male and female)
· Tennessee: Nashville
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Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
NCT07271186 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Tennessee: Chattanooga
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Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN
NCT07498335 ·
Phase: Phase 3 ·
Ages: 2 Years to 18 Years ·
Sex: All (male and female)
· Tennessee: Memphis