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A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression
NCT07112001 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Florida: Gainesville
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A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
NCT07115329 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Naples, Riverview
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A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
NCT07592689 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Maitland, Orlando, Tampa
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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
NCT03887715 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Brooksville, Hialeah, Jacksonville
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A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
NCT07172516 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Florida: Coral Gables, Gainesville, Jacksonville, Miami
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A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
NCT06775379 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Florida: Coral Springs, Hialeah, Jacksonville, Lakeland
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A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
NCT07076407 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Florida: Fort Myers, Gainesville, Riverview
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A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV
NCT06586619 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami
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A Study of Brenipatide in Adult Participants With Major Depressive Disorder
NCT07412756 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Hollywood, Maitland, Miami Gardens, Miami Lakes
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A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
NCT07573176 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Florida: Doral, Hialeah, Miami, Tampa
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A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
NCT06793397 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Maitland, Naples
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A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
NCT06696755 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Gainesville, Hollywood, Largo, Orlando
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A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
NCT04777357 ·
Phase: Phase 3 ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· Florida: Doral, Homestead, Miami, Miami Springs
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A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
NCT07276997 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Hollywood, Jacksonville, Miami, Orlando
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A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
NCT06524830 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Hollywood, Miami, Tampa
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A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
NCT07621237 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville, Maitland, Miami, Orange City
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A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
NCT07610473 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Hialeah, Orlando, Tampa
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A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
NCT07300969 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami, New Port Richey, Orlando
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A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
NCT07105111 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Bonita Springs, Hialeah, Miami, Orange City
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A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
NCT07065240 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Lauderhill, Orlando, Palm Bay
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A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
NCT06223880 ·
Phase: Phase 4 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Brandon, Doral, Hialeah, Jacksonville
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A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT07196501 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami Gardens, Orlando, Palm Bay, Tampa
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ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
NCT07284667 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Fort Myers, Hollywood, Largo, Orlando
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ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics
NCT07360600 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Tampa
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ALTO-100 in Bipolar Disorder With Depression (BD-D)
NCT06656416 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: Lauderhill
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ALTO-207 in Adults With Treatment-resistant Depression (TRD)
NCT07553637 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Saint Augustine
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Adapting Single Sessions Interventions for Type 1 Diabetes
NCT06752369 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· Florida: Orlando
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An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms
NCT07329673 ·
Phase: Not specified ·
Ages: 6 Years to 60 Years ·
Sex: All (male and female)
· Florida: Miami
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BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women
NCT07413705 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: Female
· Florida: Winter Garden
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CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
NCT05663034 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Eglin Air Force Base
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Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
NCT06132581 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Tallahassee
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Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
NCT07484217 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami
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Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Florida: Maitland, Melbourne, Miami, Port Charlotte
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Cocooned Moms Study
NCT06968650 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Florida: Miami, Tampa
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Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
NCT06595251 ·
Phase: Not specified ·
Ages: 6 Years to 14 Years ·
Sex: All (male and female)
· Florida: Miami
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E-Mindfulness Approaches for Living After Breast Cancer
NCT06748222 ·
Phase: Phase 3 ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female)
· Florida: Daytona Beach, Gainesville, Jacksonville, Tallahassee
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ENA-001 for Opioid Induced Respiratory Depression
NCT06967259 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Florida: Miami
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Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
NCT06830044 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Fort Myers, Miami, Tampa
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Families With Pride ("Familias Con Orgullo").
NCT06057337 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years to 19 Years ·
Sex: All (male and female)
· Florida: Coral Gables
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Geolocation Positional System (GPS) Experience
NCT05991713 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female)
· Florida: Coral Gables
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IMST for Dementia Risk Reduction
NCT07349706 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years to 80 Years ·
Sex: All (male and female)
· Florida: Tallahassee
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Implementing Depression and Adherence Treatment
NCT07032363 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami
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Lay-Delivered Behavioral Activation in Senior Centers
NCT04621877 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Florida: Brandon, Gibsonton, Ruskin, Tampa
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Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06966401 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hollywood, Maitland, Miami, Miami Gardens
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MBM and taVNS for Low Back Pain and Depressive Symptoms
NCT07415941 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· Florida: Tallahassee
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Mental Health in Primary Care
NCT05426057 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 16 Years ·
Sex: All (male and female)
· Florida: Miami
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Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
NCT06372964 ·
Phase: Phase 3 ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· Florida: Fort Myers, Hialeah, Homestead, Miami
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Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
NCT07494305 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Doral, Hollywood, Miami Lakes, West Palm Beach
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NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06911112 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hollywood, Miami, Tampa
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NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06963021 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Maitland, Miami, Tampa
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Neural and Psychiatric Consequences of Cannabis Use in Adolescents
NCT06941298 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 20 Years ·
Sex: All (male and female)
· Florida: Miami
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Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
NCT06559306 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Florida: Brandon, Hialeah, Homestead, Jacksonville
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Potential Benefits of Parent Child Interaction Therapy (PCIT)
NCT06827951 ·
Phase: Not specified ·
Ages: 18 Years to 89 Years ·
Sex: All (male and female)
· Florida: Gainesville, Jacksonville
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Project HOPEFUL: A PN-RCT With Implementation Science
NCT07475039 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
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RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
NCT07002034 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Tampa
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Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
NCT06633016 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Brandon, Hialeah, Jacksonville, Lake City
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Study of ALTO-300 in MDD
NCT05922878 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: Clermont, Miami Gardens, Miami Lakes, Okeechobee
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Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
NCT05850689 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Clermont, Hialeah, Miami, Tampa
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Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06786624 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hollywood, Maitland
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Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients
NCT07639359 ·
Phase: Phase 2 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Florida: Jacksonville
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Supporting Health in Veterans With Heart Failure
NCT05839067 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
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TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
NCT07048574 ·
Phase: Not specified ·
Ages: 18 Months to 11 Years ·
Sex: All (male and female)
· Florida: Hollywood, Orlando
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Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
NCT05877885 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Florida: Orlando
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The Lake Nona Life Project
NCT02533804 ·
Phase: Not specified ·
Ages: 18 Years to 110 Years ·
Sex: All (male and female)
· Florida: Orlando
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The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV
NCT05453513 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 59 Years ·
Sex: All (male and female)
· Florida: Miami
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The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program
NCT06652503 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Fort Lauderdale
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Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)
NCT05136703 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Coral Gables, Miami
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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
NCT06423430 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 70 Years ·
Sex: All (male and female)
· Florida: Tampa
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Unified Protocol: Community Connections
NCT06038721 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 7 Years to 17 Years ·
Sex: All (male and female)
· Florida: Coral Gables
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Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
NCT07221409 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Florida: Jacksonville
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Youth Emotional and Behavioral Treatment Study
NCT07296939 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 4 Years to 17 Years ·
Sex: All (male and female)
· Florida: Tallahassee
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Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
NCT06547489 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Margate, Miami, Orlando