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A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
NCT05419492 ·
Phase: Phase 1, Phase 2 ·
Ages: 6 Months to 17 Years ·
Sex: All (male and female)
· Florida: Miami
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A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
NCT06872125 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Orlando
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A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
NCT06660394 ·
Phase: Phase 3 ·
Ages: 2 Years to 65 Years ·
Sex: All (male and female)
· Florida: Gulf Breeze, Miami, Orlando, Tampa
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A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
NCT05716100 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gulf Breeze, Jacksonville
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A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
NCT04462770 ·
Phase: Phase 3 ·
Ages: 2 Years and older ·
Sex: All (male and female)
· Florida: Kissimmee, Winter Park
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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
NCT06132893 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Boca Raton, Bradenton, Jacksonville, Miami
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A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
NCT05667142 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Orlando, Pensacola
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AI-Based Mobile Intervention on Medication Non-Adherence and Transition
NCT07445074 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 24 Years ·
Sex: All (male and female)
· Florida: Orlando
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AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
NCT06063850 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Jacksonville
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Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery
NCT06280092 ·
Phase: Early Phase 1 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Jacksonville
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An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
NCT05066217 ·
Phase: Phase 3 ·
Ages: 2 Years to 55 Years ·
Sex: All (male and female)
· Florida: Miami, Orlando, Winter Park
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An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy
NCT07509177 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: North Miami
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An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures
NCT06908356 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami Lakes
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Diagnosing Epilepsy To EffeCT Change
NCT07110337 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Tampa
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Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
NCT07110454 ·
Phase: Not specified ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Tampa
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Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
NCT07051629 ·
Phase: Phase 1 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: DeLand, Tamarac, Weston
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Impact of Capturing Ictal Events With Ultra-long-term Ambulatory EEG Monitoring With Remote EEG Monitoring System.
NCT06027749 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: Tampa
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Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
NCT05219617 ·
Phase: Phase 3 ·
Ages: 4 Years to 55 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Orlando, Tampa, Wellington
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Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
NCT02216500 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: Up to 50 Years ·
Sex: All (male and female)
· Florida: Gainesville
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Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
NCT04419272 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami
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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Florida: Gainsville
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RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures
NCT06798896 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: Port Charlotte
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SPN-817 Open-Label Extension Study in Adults With Focal Onset Seizures
NCT07141329 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Port Charlotte
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Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy
NCT05518578 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami
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Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures
NCT07594119 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Maitland, Miami
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Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
NCT07563881 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Gulf Breeze
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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
NCT05135091 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami