Clinical trials recruiting for Epilepsy
350
Recruiting trials
42
US states with sites
52
Countries
16%
Accept healthy volunteers
Phase breakdown
Drugs and treatments being studied
| Intervention | Trials |
|---|---|
| Levetiracetam | 5 |
| Cenobamate | 3 |
| RAP-219 | 3 |
| SPN-817 | 3 |
| ABS-1230 | 2 |
| Clemizole HCl | 2 |
| Exogenous ketone ester | 2 |
| Ketamine | 2 |
| Midazolam | 2 |
| NRTX-1001 | 2 |
| Phenytoin | 2 |
| Sirolimus | 2 |
Where trials are recruiting (top US states)
| State | Recruiting trials |
|---|---|
| Texas | 41 |
| California | 37 |
| New York | 33 |
| Massachusetts | 32 |
| Florida | 27 |
| Ohio | 25 |
| North Carolina | 23 |
| Minnesota | 22 |
| Maryland | 21 |
| Pennsylvania | 21 |
| Michigan | 17 |
| Alabama | 15 |
Top cities
Boston, Massachusetts 28Houston, Texas 28New York, New York 24Philadelphia, Pennsylvania 18Durham, North Carolina 17Rochester, Minnesota 17Bethesda, Maryland 16Los Angeles, California 15Aurora, Colorado 14Birmingham, Alabama 13
Self-screener
Recruiting trials
- A Clinical Study on the Efficacy and Safety of Zonisamide as a First Add-On Treatment in Epileptic Seizures
- A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
- A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
- A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
- A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
- A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
- A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures
- A Multicenter Pediatric Deep Brain Stimulation Registry
- A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders
- A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
- A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome
- A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
- A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
- A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy
- A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
- A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes
- A Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease
- A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
- A Study Evaluating NPT 2042 Versus Placebo in Subjects Aged 16-75 Years With Genetic Generalized Epilepsy (GGE) and Absence Seizures
- A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
- A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
- A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
- A Study to Evaluate the Safety and Pharmacokinetics of RC001 in Children With Dravet Syndrome
- A Study to Evaluate the Safety, Efficacy, and PK of ONO-2017 in Japanese Patients With POS 2 to 17 Year Olds
- A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of ABS-1230 in Pediatric and Young Adult Participants With KCNT1-related Epilepsy
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ABS-1230 Given Orally Compared With Placebo in Healthy Participants Aged 18 to 55 Years
- A Study to Prevent Infantile Spasms Relapse
- A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
- A Survey of Midazolam in People With Status Epilepticus
- AI-Based Mobile Intervention on Medication Non-Adherence and Transition
- AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
- ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome
- Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on the Efficacy of Amiloride in the Prophylaxis of Migraine Aura
- Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery
- Amygdala Memory Enhancement
- An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
- An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy
- An Observational Study of Epilepsy: Biology and Outcomes Using Real-world Data
- An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures
- An Open-label Study to Evaluate Safety, Tolerability, and Efficacy of CB03-154 in Subjects Diagnosed With Epilepsy
- Antiepileptic Drugs in Elderly Patients
- Assessment of Kidney Function in Patients With Epilepsy
- Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age
- Atlas of Human Cognition by SEEG (MAPCOG-SEEG)
- B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy
- BMB-101 in Absence Epilepsy and DEE
- Baker Gordon Syndrome Natural History Study
- Biology of Juvenile Myoclonic Epilepsy
- Biomarkers of Response to SEEG Thermocoagulation
- Biperiden Trial for Epilepsy Prevention
- Bone Management in Pregnancy Outcomes in Epilepsy
- Brain Activity in Epilepsy
- Brain Development Research Program
- Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease
- Brain Representation of Acquisition in Humans of Motor-Sensory Skills
- Breathing Rescue for SUDEP Prevention
- Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes
- Bridging the Treatment Gap by Expanding Access to Care for People With Epilepsy in Kenya (BEACON)
- Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy
- Cannabidiol as add-on Therapy for Children With Refractory Epilepsy (CBD-uN1que), a High-quality Individualized Approach: a Series of N-of-1 Trials
- Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings
- Caracterization of the Combined Alterations in Respiration and aROUSal in Patients With Drug-resistant EpiLepsy
- Carbon Dioxide (CO2) Chemosensitivity and SUDEP
- Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy
- Changes in Attentional Control After a Focal Seizure.
- Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy
- Characterization by Automated System on Infantile Spasmes
- Chinese-Specific Speech Imagery Coding Using High-Density ECoG
- Clinic-based and Technology-Supported Sleep Intervention for Pediatric Epilepsy
- Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease
- Clinical Evaluation of the Efficacity of Epilepsy Surgery in Infants and Children
- Clinical Outcomes of Pregnant Individuals With Epilepsy - Prospective Study
- Clinical Study Evaluating Safety of Pentoxifylline and Celecoxib in Patients With Grand-Mal Epilepsy Treated by Phenytoin Monotherapy
- Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy
- Cognitive and Electrophysiological Assessment of Non-Invasive Temporally-Interfering Electric Fields Stimulation (TIEFS)
- Collaborative Care for Anxiety and Depression in Epilepsy
- Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
- Computational Neuroscience of Language Processing in the Human Brain
- Congenital Muscle Disease Study of Patient and Family Reported Medical Information
- Contribution of Fast-ripples to the Improvement of the Neurosurgical Management of Drug-refractory Epilepsy
- Creation of a Database of Healthy Subjects With 18FDG PET Brain Imaging as Part of the MOBILE Project (Multimodal Whole-Brain Imaging in Epilepsy)
- Creation of a Register of Patients With Neonatal-onset Epileptic Encephalopathy
- De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical Information
- Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data
- Diagnosing Epilepsy To EffeCT Change
- Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
- Diffusion Tensor and Functional Connectivity Imaging in Pediatric Epilepsy: Imaging/Histology Correlation
- Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System
- Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
- EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
- EPC Performance Investigation for StereoElectroEncephaloGraphy
- EPIGUT: EPILEPSY AND GASTROINTESTINAL MICROBIOTA: UNDERSTANDING THERAPY RESPONSE
- ESIS in Pediatric DRE
- Ear-Seizure Detection (EarSD) Study
- Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)
- Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy
- Effect of Cognitive Behavioral Play Intervention and Epilepsy
- Effect of GABA on ADHD and Seizures in Children With Epilepsy.
- Effect of Rose Odor Exposure on Ictal Apnea
- Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
Related conditions
Trials recruiting for Epilepsy often also study these conditions. Each links to its own recruiting-trial list.
Drug Resistant Epilepsy 28Focal Epilepsy 17Depression 1463Seizures 15Dravet Syndrome 11Epilepsy, Temporal Lobe 10Multiple sclerosis 445Epilepsy in Children 9Anxiety 1237Refractory Epilepsy 7
Common questions
Are these trials free to join?
Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.
How do I know if I am eligible for Epilepsy trials?
Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.
Is this list complete?
No. For the full list, search ClinicalTrials.gov.