Phase 1 Epilepsy trials recruiting now

All Epilepsy trials, every phase

Other phases for Epilepsy

Phase 1 Epilepsy trials

• A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
  NCT05419492 · Phase: Phase 1, Phase 2 · Ages: 6 Months to 17 Years · Sex: All (male and female) · 14 locations
• A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
  NCT07227857 · Phase: Phase 1, Phase 2 · Ages: 2 Years to 12 Years · Sex: All (male and female) · 15 locations
• A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
  NCT06422923 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 17 locations
• A Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease
  NCT06609889 · Phase: Phase 1, Phase 2 · Ages: 10 Years to 18 Years · Sex: All (male and female) · 1 location
• A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
  NCT06388707 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ABS-1230 Given Orally Compared With Placebo in Healthy Participants Aged 18 to 55 Years
  NCT07156201 · Phase: Phase 1 · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
  NCT06063850 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 36 locations
• ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome
  NCT07531745 · Phase: Phase 1, Phase 2 · Ages: 2 Years to 12 Years · Sex: All (male and female) · 6 locations
• Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
  NCT07051629 · Phase: Phase 1 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 10 locations
• Effects of a Sigle Dose of Ayahuasca in Patients With Psychogenic Non-epileptic Seizures: an Open Label Clinical Trial
  NCT07747324 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Glutamate Inhibitors in Glioblastoma
  NCT05664464 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder
  NCT07102524 · Phase: Phase 1, Phase 2 · Ages: 2 Years to 20 Years · Sex: All (male and female) · 1 location
• Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
  NCT02531880 · Phase: Phase 1 · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies
  NCT06700811 · Phase: Phase 1 · Ages: 0 Days to 9 Months · Sex: All (male and female) · 1 location
• Microelectrode Recordings From the Vagus Nerve in Awake Humans
  NCT06016686 · Phase: Phase 1 · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders.
  NCT07363603 · Phase: Phase 1, Phase 2 · Ages: 1 Year to 14 Years · Sex: All (male and female) · 1 location
• Understanding Ketamine's Dissociative Effects (KD Study)
  NCT04861051 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location

Common questions

What does Phase 1 mean?

See how clinical trials work.

Is this list complete?

No. For the full record, search ClinicalTrials.gov.