Heart failure trials recruiting in California

All Heart failure trials nationally

Cities in California

Recruiting trials in California

• A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
  NCT07137338 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · California: San Diego
• A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
  NCT03394365 · Phase: Phase 3 · Ages: No age limits stated · Sex: All (male and female) · California: Duarte, La Jolla, Loma Linda, Los Angeles
• A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
  NCT05489705 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: La Jolla, Los Angeles, Palo Alto, San Francisco
• A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
  NCT06979362 · Phase: Phase 2 · Ages: 40 Years to 84 Years · Sex: All (male and female) · California: Covina, La Jolla, Northridge, San Francisco
• A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
  NCT07567001 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Alhambra, Beverly Hills, Chula Vista, Concord
• A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
  NCT07219511 · Phase: Phase 1 · Ages: 50 Years and older · Sex: All (male and female) · California: Huntington Beach, Santa Maria, Van Nuys
• A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
  NCT07795814 · Phase: Phase 2 · Ages: 30 Years to 84 Years · Sex: All (male and female) · California: Beverly Hills, San Diego, Vista
• A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
  NCT06056297 · Phase: Phase 3 · Ages: 12 Years and older · Sex: All (male and female) · California: Irvine, La Jolla, Los Angeles, Torrance
• A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
  NCT06024746 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Chula Vista, El Centro, Sacramento, San Francisco
• A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
  NCT06008197 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Chula Vista, Huntington Beach, Los Angeles, Sacramento
• A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
  NCT06033950 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Chula Vista, Northridge, Orange, Pomona
• A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
  NCT07761117 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Beverly Hills, Huntington Beach, Huntington Park, Loma Linda
• A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
  NCT06991257 · Phase: Phase 2 · Ages: 18 Years to 79 Years · Sex: All (male and female) · California: Beverly Hills, Lake Forest, Santa Maria
• A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
  NCT06935370 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Beverly Hills, Covina, Encinitas, Merced
• A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
  NCT06424288 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Chula Vista, Orange, San Dimas, Santa Clarita
• A Trial of CRD-4730 in HFrEF
  NCT07750873 · Phase: Phase 2 · Ages: 18 Years to 85 Years · Sex: All (male and female) · California: Pasadena
• AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
  NCT06699056 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: Orange, Pasadena
• AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
  NCT06793371 · Phase: Phase 2 · Ages: 40 Years to 85 Years · Sex: All (male and female) · California: Imperial, Pasadena, San Francisco, Santa Maria
• AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
  NCT06378632 · Phase: Not specified · Ages: 22 Years and older · Sex: All (male and female) · California: La Jolla, Loma Linda, San Diego, San Francisco
• Alleviant ALLAY-HF Study
  NCT05685303 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · California: Long Beach, Sacramento, San Diego, San Francisco
• Alleviant ALLAY-HFrEF Study
  NCT06812533 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles, Sacramento, San Diego, San Francisco
• Allograft Dysfunction in Heart Transplant
  NCT03102125 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · California: La Jolla
• Assessment of CCM in HF With Higher Ejection Fraction
  NCT05064709 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Concord, La Jolla, Los Angeles, Northridge
• At-Home Cardiac Rehabilitation for Adolescents at Risk for Heart Failure
  NCT06826534 · Phase: Not applicable (e.g. observational or device study) · Ages: 0 Years to 21 Years · Sex: All (male and female) · California: Los Angeles
• CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
  NCT07207811 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: La Jolla, Los Angeles, Orange, Pasadena
• CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
  NCT05996328 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · California: Long Beach, Palo Alto, West Los Angeles
• CardioMEMS HF System Coverage With Evidence Development Study
  NCT06779552 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: Pleasanton
• Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
  NCT04262830 · Phase: Not specified · Ages: 13 Years to 39 Years · Sex: All (male and female) · California: San Diego
• Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
  NCT05485961 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Bakersfield, Beverly Hills, Chula Vista, Fresno
• Developing a Digital Aid to Improve ICD Decisions
  NCT07084142 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · California: San Francisco
• Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
  NCT05677100 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years and older · Sex: All (male and female) · California: Concord, San Francisco
• ELEVATE-HFpEF Clinical Study
  NCT06678841 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · California: San Francisco
• Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
  NCT01790152 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · California: Duarte, Madera, Oakland, Palo Alto
• Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
  NCT05714085 · Phase: Phase 2, Phase 3 · Ages: 29 Days to 17 Years · Sex: All (male and female) · California: Los Angeles, Palo Alto, San Bernardino
• Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
  NCT04592445 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · California: La Jolla, San Francisco
• Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
  NCT05650541 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Palm Springs
• Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
  NCT06898515 · Phase: Phase 3 · Ages: 22 Years and older · Sex: All (male and female) · California: Irvine, La Jolla, Sacramento
• HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
  NCT06425848 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · California: La Jolla
• Heart Failure Precision Medicine Study
  NCT04196842 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years and older · Sex: All (male and female) · California: Sacramento
• HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
  NCT05873634 · Phase: Not specified · Ages: 30 Years and older · Sex: All (male and female) · California: Sacramento
• His-Bundle Corrective Pacing in Heart Failure
  NCT05265520 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles
• Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
  NCT06039176 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · California: San Francisco
• Identifying Markers of Exercise Training in Heart Failure
  NCT05696652 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 89 Years · Sex: All (male and female) · California: Stanford
• Impact of Barostimulation on Hemodynamics in Adults With Heart Failure
  NCT07335510 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: San Francisco
• Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
  NCT06526988 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Walnut Creek
• Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure
  NCT07467668 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Pleasanton
• Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
  NCT06310031 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 100 Years · Sex: All (male and female) · California: Los Angeles
• LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
  NCT07288398 · Phase: Phase 3 · Ages: 18 Years to 85 Years · Sex: All (male and female) · California: Sacramento, San Francisco, Stanford, Torrance
• Left vs Left Randomized Clinical Trial
  NCT05650658 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: La Jolla
• Levothyroxine Supplementation for Heart Transplant Recipients
  NCT06428097 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · California: San Francisco
• MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
  NCT05933083 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: San Francisco
• MYTHS - MYocarditis THerapy With Steroids
  NCT05150704 · Phase: Phase 3 · Ages: 18 Years to 69 Years · Sex: All (male and female) · California: San Diego
• Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
  NCT07037459 · Phase: Phase 3 · Ages: 18 Years to 99 Years · Sex: All (male and female) · California: Beverly Hills, Covina, Huntington Beach, Inglewood
• Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
  NCT04703842 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · California: San Diego, San Francisco
• Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
  NCT06929806 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · California: Pasadena
• Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
  NCT06080074 · Phase: Phase 2 · Ages: 0 Years to 16 Years · Sex: All (male and female) · California: Palo Alto
• NORM-HF Pivotal Study
  NCT07574593 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Chula Vista, Sacramento
• Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
  NCT06311708 · Phase: Not specified · Ages: 14 Years to 65 Years · Sex: All (male and female) · California: San Francisco
• OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
  NCT06939751 · Phase: Not specified · Ages: 18 Years to 99 Years · Sex: All (male and female) · California: Los Angeles, Palo Alto
• Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
  NCT06228924 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · California: San Francisco
• PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
  NCT05934487 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles, San Francisco
• Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
  NCT04278404 · Phase: Not specified · Ages: 0 Years to 20 Years · Sex: All (male and female) · California: Los Angeles, Palo Alto
• Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
  NCT06677060 · Phase: Phase 3 · Ages: 40 Years and older · Sex: All (male and female) · California: Dublin, Huntington Beach, Inglewood, La Jolla
• Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
  NCT00271180 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · California: Bakersfield, Chula Vista, La Jolla, Los Angeles
• REHAB Fontan Failure: A Trial of Cardiac Rehabilitation
  NCT06150950 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Stanford
• REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
  NCT06777368 · Phase: Not specified · Ages: 18 Years to 105 Years · Sex: All (male and female) · California: Los Angeles, Sacramento, Stanford, Thousand Oaks
• Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
  NCT06360380 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 79 Years · Sex: All (male and female) · California: La Jolla, San Francisco
• Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure
  NCT03586336 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: San Francisco
• Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
  NCT07690436 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: Palo Alto
• Right Ventricular Pacing in Pulmonary Arterial Hypertension
  NCT04194632 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · California: San Francisco
• Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
  NCT07069738 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: La Jolla, Los Angeles, Oakland, Santa Monica
• Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
  NCT07059962 · Phase: Not specified · Ages: 21 Years and older · Sex: All (male and female) · California: Victorville
• Simulation Trial of Telemedical Support for Paramedics
  NCT06441760 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years and older · Sex: All (male and female) · California: Los Angeles
• Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
  NCT06217302 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · California: Stanford
• Staged Kidney Transplantation During Combined Heart/Kidney Transplantation
  NCT06877169 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles
• Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
  NCT06736574 · Phase: Phase 3 · Ages: 18 Years to 85 Years · Sex: All (male and female) · California: Beverly Hills, La Jolla, Loma Linda, Los Angeles
• Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
  NCT06597019 · Phase: Phase 3 · Ages: 6 Years to 11 Years · Sex: All (male and female) · California: San Francisco
• Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
  NCT06597006 · Phase: Phase 3 · Ages: 2 Years to 11 Years · Sex: All (male and female) · California: San Francisco
• Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
  NCT06307652 · Phase: Phase 3 · Ages: 18 Years to 130 Years · Sex: All (male and female) · California: Beverly Hills, Covina, Encinitas, Los Angeles
• TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
  NCT06137807 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: San Diego, San Francisco
• The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
  NCT05427370 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles
• The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
  NCT03142152 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Long Beach, Los Angeles, Redwood City, San Diego
• The STOP-MED CTRCD Trial
  NCT06183437 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles
• Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients
  NCT03383419 · Phase: Phase 2 · Ages: 18 Years to 90 Years · Sex: All (male and female) · California: Los Angeles
• Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
  NCT07221851 · Phase: Phase 3 · Ages: 2 Years to 17 Years · Sex: All (male and female) · California: Palo Alto, Sacramento
• Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
  NCT06526195 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: Sacramento, San Francisco
• Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
  NCT05459233 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: San Francisco
• Voice Analysis to Detect Pulmonary Arterial Pressure Changes in Heart Failure
  NCT07443670 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: San Francisco
• WISE CVD - Continuation (WISE HFpEF)
  NCT02582021 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles
• Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
  NCT03876223 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · California: Los Angeles
• XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
  NCT06895070 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · California: La Jolla, Los Angeles, Stanford