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: Vascular Function in Health and Disease
NCT02966665 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Murray
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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
NCT06056297 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
NCT06024746 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Layton
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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
NCT06033950 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Layton
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A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
NCT07192952 ·
Phase: Phase 3 ·
Ages: Up to 18 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
NCT07188805 ·
Phase: Phase 3 ·
Ages: 6 Months to 17 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
NCT01099982 ·
Phase: Not specified ·
Ages: 13 Years and older ·
Sex: All (male and female)
· Utah: Murray, Salt Lake City
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CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Murray
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CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
NCT05996328 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
NCT06964464 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
NCT05677100 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Utah: Murray
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Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
NCT06291922 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
NCT06526988 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
NCT06310031 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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LVAD Conditioning for Cardiac Recovery
NCT03238690 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Left vs Left Randomized Clinical Trial
NCT05650658 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Muscle Blood Flow Regulation in HFpEF
NCT05115890 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)
NCT04600115 ·
Phase: Early Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Novel Approaches for Improving Vascular Function in Veterans With HFpEF
NCT06312748 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
NCT06677060 ·
Phase: Phase 3 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Utah: Clearfield, Ogden
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Simulation Trial of Telemedical Support for Paramedics
NCT06441760 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
NCT06271577 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Murray
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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
NCT06736574 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Utah: Murray, Salt Lake City
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Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
NCT06597019 ·
Phase: Phase 3 ·
Ages: 6 Years to 11 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
NCT06597006 ·
Phase: Phase 3 ·
Ages: 2 Years to 11 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652 ·
Phase: Phase 3 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· Utah: Salt Lake City
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TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
NCT06137807 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Murray
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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City
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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Utah: Salt Lake City