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A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
NCT07266831 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte, Greensboro
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A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
NCT07044297 ·
Phase: Phase 3 ·
Ages: 16 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill, Greensboro
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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
NCT05719441 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· North Carolina: Chapel Hill, Greensboro
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A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)
NCT07202546 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte, Durham, Greensboro, Wilmington
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A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma
NCT04139304 ·
Phase: Early Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill
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A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV
NCT07143968 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Durham
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A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
NCT07650916 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· North Carolina: Greensboro
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Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
NCT05129345 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte, Durham
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Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.
NCT00404989 ·
Phase: Not specified ·
Ages: 12 Years to 60 Years ·
Sex: Female
· North Carolina: Wilmington
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Appalachian Partnership to Reduce Disparities (Aim 2)
NCT04378439 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Winston-Salem
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Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP
NCT07218211 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: Male
· North Carolina: Durham
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Enhancing Wellness Through Affirming Services and Education
NCT05700474 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Charlotte
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Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1
NCT06071767 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill
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Food as Medicine for HIV and Diabetes
NCT05026723 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill
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Gathering Online for Dialogue and Discussion to Enhance Social Support
NCT05753683 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 30 Years ·
Sex: All (male and female)
· North Carolina: Durham
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Human Immunodeficiency Virus (HIV) Food Insecurities
NCT04943861 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Winston-Salem
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Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older
NCT05858034 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· North Carolina: Winston-Salem
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Menopausal HT for Women Living With HIV (HoT)
NCT06856174 ·
Phase: Phase 4 ·
Ages: 40 Years to 60 Years ·
Sex: Female
· North Carolina: Chapel Hill, Greensboro
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Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
NCT04810858 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 59 Years ·
Sex: All (male and female)
· North Carolina: Winston-Salem
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Observational Pharmaco-Epidemiology Research & Analysis
NCT03813862 ·
Phase: Not specified ·
Ages: 0 Years and older ·
Sex: All (male and female)
· North Carolina: Durham
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Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care
NCT05241990 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Chapel Hill
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Project neuroARTEMIS
NCT06814275 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 59 Years ·
Sex: All (male and female)
· North Carolina: Winston-Salem
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Quitting Matters Human Immunodeficiency Virus Hybrid Trial
NCT06883097 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· North Carolina: Winston-Salem
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SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families
NCT06627764 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 100 Years ·
Sex: All (male and female)
· North Carolina: Durham
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Small Trial of Alendronate Impact on the Reservoir of HIV
NCT07216794 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· North Carolina: Chapel Hill
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Using PrEP, Doing It for Ourselves
NCT06638892 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· North Carolina: Durham