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A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
NCT07266831 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
NCT07044297 ·
Phase: Phase 3 ·
Ages: 16 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
NCT05719441 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma
NCT04139304 ·
Phase: Early Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
NCT07390955 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
NCT07650916 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies
NCT07569029 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
NCT06665646 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV
NCT07390474 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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Enhancing the Organizational Social Context to Improve Viral Suppression and Retention in HIV Care
NCT06462807 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1
NCT06071767 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
NCT05077527 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study
NCT04949464 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years to 80 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
NCT07473778 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Intervention to Improve Parent Communication About Sexuality
NCT07672067 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 100 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
NCT06263426 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia, Pittsburgh
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Menopausal HT for Women Living With HIV (HoT)
NCT06856174 ·
Phase: Phase 4 ·
Ages: 40 Years to 60 Years ·
Sex: Female
· Pennsylvania: Philadelphia, Pittsburgh
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Point of Care STI Testing
NCT06844045 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 16 Years to 24 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV
NCT05502653 ·
Phase: Not specified ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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Screen Smart: Using Digital Health to Improve HIV Screening and Prevention
NCT06003192 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 15 Years to 21 Years ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Small Trial of Alendronate Impact on the Reservoir of HIV
NCT07216794 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Pennsylvania: Pittsburgh
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Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships
NCT07246057 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 16 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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The Collaborative Care PrTNER Study
NCT06585631 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 15 Years to 29 Years ·
Sex: Male
· Pennsylvania: Philadelphia
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Transitional Housing and HIV Health
NCT06829394 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Trial of Ixazomib for Kaposi Sarcoma
NCT04305691 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Pennsylvania: Philadelphia
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Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission
NCT02140255 ·
Phase: Phase 1, Phase 2 ·
Ages: Up to 48 Hours ·
Sex: All (male and female)
· Pennsylvania: Philadelphia