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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Fairhope
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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
NCT07142356 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Alabama: Alexander City
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A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
NCT07610278 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Alabama: Foley, Saraland
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Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
NCT07240831 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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Arterial Stiffness and Blood Pressure
NCT06495710 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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CARBON: UAB Cardiovascular Research Biobank
NCT05067231 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project
NCT05989581 ·
Phase: Phase 1 ·
Ages: 14 Years to 89 Years ·
Sex: Female
· Alabama: Birmingham
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De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
NCT05213676 ·
Phase: Phase 4 ·
Ages: 0 Months to 1 Month ·
Sex: All (male and female)
· Alabama: Birmingham
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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Anniston, Fairhope, Guntersville
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Early Time-Restricted Eating in Older Adults With Hypertension
NCT07135505 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
NCT06468202 ·
Phase: Phase 4 ·
Ages: 14 Years to 35 Years ·
Sex: Female
· Alabama: Birmingham
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Exosome Cargo From Preeclampsia Patients
NCT04154332 ·
Phase: Not specified ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Alabama: Birmingham
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Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults
NCT04396002 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Alabama: Birmingham
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Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers
NCT06629649 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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Inspire HER: Inspiring the Heart and Emotions for Radical Health
NCT06966258 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 30 Years to 79 Years ·
Sex: Female
· Alabama: Birmingham
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Alabama: Alexander City
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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
NCT04971720 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham
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Polygenic Risk Score Implementation and Stratification for Managing Blood Pressure
NCT06962488 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Alabama: Birmingham
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Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
NCT06373289 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 1 Month to 5 Months ·
Sex: All (male and female)
· Alabama: Birmingham
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Renal Pelvic Denervation Pilot Trial
NCT07005050 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· Alabama: Birmingham
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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NCT06559891 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 75 Years ·
Sex: All (male and female)
· Alabama: Birmingham
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The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.
NCT05676476 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 49 Years ·
Sex: Female
· Alabama: Birmingham
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Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
NCT05556902 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 89 Years ·
Sex: All (male and female)
· Alabama: Birmingham
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Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
NCT07495852 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Dothan
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Ventilator Pressure and Optimization of Compliance and Hemodynamics
NCT06512935 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 7 Days to 30 Days ·
Sex: All (male and female)
· Alabama: Birmingham
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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Alabama: Birmingham, Fairhope, Foley, Huntsville