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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Braintree, New Bedford, Worcester
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A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia
NCT07312227 ·
Phase: Not specified ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Massachusetts: Boston
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A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
NCT07142356 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
NCT07333183 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases
NCT07780890 ·
Phase: Not specified ·
Ages: 20 Years to 79 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
NCT06649110 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Burlington
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A Trial of Hydrus Microstent Versus Goniotomy
NCT06289491 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
NCT07365332 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
NCT06129240 ·
Phase: Not specified ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement
NCT07091851 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 35 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
NCT05937854 ·
Phase: Phase 2 ·
Ages: 35 Years to 89 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia
NCT07238400 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: Female
· Massachusetts: Boston
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Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study
NCT05030545 ·
Phase: Phase 4 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Clarifying the Optimal Application of SLT Therapy Trial
NCT04967989 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Reading
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Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
NCT04835857 ·
Phase: Not specified ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Massachusetts: Newton
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Data Gathering for A10900
NCT07149740 ·
Phase: Not specified ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Massachusetts: Wellesley Hills
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De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
NCT05213676 ·
Phase: Phase 4 ·
Ages: 0 Months to 1 Month ·
Sex: All (male and female)
· Massachusetts: Boston
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Malden, Methuen
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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)
NCT07290244 ·
Phase: Phase 1 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
NCT06557005 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Massachusetts: Boston
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Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
NCT05924477 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Global Paradise System US Post Approval Study
NCT06297291 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Groceries for Residents of Southeastern USA to Stop Hypertension
NCT06891911 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Home Hospital for Suddenly Ill Adults
NCT03524222 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
NCT06948838 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Quincy, Roslindale
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LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT05798923 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation
NCT07174622 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension
NCT05593055 ·
Phase: Phase 4 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Moms@Home: A Storytelling-based Mobile Health Intervention to Improve Blood Pressure Management in Pregnancy
NCT06835959 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 50 Years ·
Sex: Female
· Massachusetts: Worcester
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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Non-Invasive Preeclampsia Screening and Biobank
NCT06643741 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: Female
· Massachusetts: Boston
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PRESSURE CHECK: Find Your Path to Better Health
NCT06122246 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
NCT02249923 ·
Phase: Not specified ·
Ages: 1 Day to 21 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Lexington
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Remote Fetal Monitoring in High Risk Pregnancies
NCT06822439 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: Female
· Massachusetts: Boston
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SPYRAL GEMINI Pilot Study
NCT06907147 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Social Needs Screening and Chronic Diseases Study (WE CARE)
NCT06903897 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: No age limits stated ·
Sex: All (male and female)
· Massachusetts: Worcester
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Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories
NCT07041281 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: Female
· Massachusetts: Boston
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Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
NCT07318597 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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The Glaucoma and Retinopathy Screening Study
NCT06882356 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Chelsea, Lynn, Salem
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Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
NCT05884190 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Massachusetts: Worcester
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Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
NCT04555161 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis
NCT06265272 ·
Phase: Not specified ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Massachusetts: Charlestown
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Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension
NCT06554340 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
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WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control
NCT07523269 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Wearable Evaluation of Ambulatory Readings for Blood Pressure
NCT06610448 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Massachusetts: Boston
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Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Hypertension Receiving Bevacizumab for Breast Cancer
NCT02610413 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Massachusetts: Boston