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24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
NCT07325240 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
NCT07218029 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis
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A Pilot Study of Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in Pulmonary Arterial Hypertension (GUT RESTORE-PAH)
NCT06481852 ·
Phase: Phase 1 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Minnesota: Minneapolis
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A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)
NCT06150560 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
NCT06822738 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
NCT07240831 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
NCT06129240 ·
Phase: Not specified ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy
NCT06886087 ·
Phase: Not specified ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Minnesota: Rochester
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Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
NCT04439370 ·
Phase: Not specified ·
Ages: 35 Years to 70 Years ·
Sex: Female
· Minnesota: Minneapolis
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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Bloomington, Minneapolis, Rochester
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CVD/PH and Voice Characteristics
NCT07311044 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
NCT06402968 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Minnesota: Saint Cloud
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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Dose-Response Effects of Inspiratory Muscle Strength Training on Blood Pressure and Vascular Function
NCT07109739 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
NCT06526858 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 80 Years ·
Sex: All (male and female)
· Minnesota: Rochester
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Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
NCT06507657 ·
Phase: Early Phase 1 ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study
NCT06151730 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Minnesota: Rochester
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Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)
NCT03138863 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 50 Years ·
Sex: Female
· Minnesota: Rochester
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Glaucoma Laser Assessment of Stability and Sustainability
NCT06963684 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Minnesota: Coon Rapids
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Global Paradise System US Post Approval Study
NCT06297291 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Coon Rapids
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HOPE-BP 2.0: Evaluating the Optimal Duration of Postpartum Remote Blood Pressure Monitoring
NCT07204756 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Minnesota: Minneapolis
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HTN App for HTN Control and Cardiovascular Health Among African-Americans
NCT06346886 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Minnesota: Rochester
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Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Minnesota: Coon Rapids
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Minnesota: Minneapolis, Rochester
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Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial
NCT06826755 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 55 Years ·
Sex: Female
· Minnesota: Rochester
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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
NCT04046523 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 4 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Obstructive Sleep Apnea Among Somali-Americans
NCT04124848 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Minnesota: Minneapolis
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Pulmonary Hypertension Association Registry
NCT04071327 ·
Phase: Not specified ·
Ages: 0 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis, Rochester
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Pulmonary Hypertension in Left Heart Disease
NCT05935605 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
NCT06333652 ·
Phase: Phase 2 ·
Ages: 18 Years to 50 Years ·
Sex: Female
· Minnesota: Rochester
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Real World Observational Study of Sotatercept for Pulmonary Hypertension
NCT06751082 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Renal Pelvic Denervation Pilot Trial
NCT07005050 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 80 Years ·
Sex: All (male and female)
· Minnesota: Minneapolis, Rochester
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Sleep Restriction and Parental History of Hypertension
NCT06482814 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 35 Years ·
Sex: All (male and female)
· Minnesota: Rochester
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Study of Disrupted Sleep in Somali Americans
NCT05411029 ·
Phase: Not specified ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Minnesota: Rochester
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Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
NCT04555161 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis, Rochester
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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Minneapolis, Rochester
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Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension
NCT06797193 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Rochester
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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Minnesota: Richfield, Saint Cloud