-
2-HOBA in Systemic Lupus Erythematosus
NCT07225543 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: Female
· Tennessee: Nashville
-
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga, Knoxville, Nashville
-
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
NCT06843577 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Tennessee: Cleveland
-
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
NCT06649110 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Tennessee: Knoxville
-
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
NCT07365332 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Arterial Stiffness and Blood Pressure
NCT06495710 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
NCT05401357 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Germantown, Nashville
-
CPAP for the Treatment of Supine Hypertension
NCT05489575 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Cardiometabolic Disease and Substrate Metabolism
NCT07565727 ·
Phase: Not specified ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Tennessee: Knoxville
-
Clarifying the Optimal Application of SLT Therapy Trial
NCT04967989 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults
NCT05955339 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
Data Gathering for A10900
NCT07149740 ·
Phase: Not specified ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Tennessee: Germantown
-
De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia
NCT05213676 ·
Phase: Phase 4 ·
Ages: 0 Months to 1 Month ·
Sex: All (male and female)
· Tennessee: Memphis, Nashville
-
DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville
-
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville
-
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
NCT04502225 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Exercise Testing After Preeclampsia
NCT06741436 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: Female
· Tennessee: Nashville
-
Global Paradise System US Post Approval Study
NCT06297291 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
Gut Microbiota in Metabolic Surgery
NCT05000996 ·
Phase: Not specified ·
Ages: 21 Years to 65 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Hormonal, Metabolic, and Signaling Interactions in PAH
NCT01884051 ·
Phase: Not specified ·
Ages: Up to 90 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension
NCT07563322 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Metabolic Effects of Angiotensin-(1-7)
NCT02646475 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Mobile Health Intervention to Improve Exercise in Pediatric PH
NCT06549452 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 10 Years to 21 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville
-
Non-Invasive Preeclampsia Screening and Biobank
NCT06643741 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: Female
· Tennessee: Chattanooga
-
Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension
NCT03042988 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
NCT02249923 ·
Phase: Not specified ·
Ages: 1 Day to 21 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville, Memphis
-
Pulmonary Hypertension Association Registry
NCT04071327 ·
Phase: Not specified ·
Ages: 0 Years and older ·
Sex: All (male and female)
· Tennessee: Knoxville, Nashville
-
Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia
NCT06802861 ·
Phase: Not specified ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Tennessee: Knoxville
-
Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)
NCT05462574 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
NCT05584722 ·
Phase: Not specified ·
Ages: 15 Years to 80 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
NCT07511361 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga
-
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
NCT05587712 ·
Phase: Phase 2 ·
Ages: 1 Year to 17 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Sympathetic Mechanisms in Obesity-Crossover Design
NCT05312892 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Team Lifestyle Immersion Hypertension Control Project
NCT07201948 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 30 Years to 80 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
The MObile Health InterVEntion in Pulmonary Arterial Hypertension (MOVE PAH) Study
NCT05464095 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Nashville
-
Treatment of Supine Hypertension in Autonomic Failure (CPAP)
NCT03312556 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Tennessee: Nashville
-
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Memphis
-
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Tennessee: Chattanooga, Knoxville