-
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
NCT07115329 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Massachusetts: Worcester
-
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
NCT07592689 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Worcester
-
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
NCT06775379 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Springfield
-
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
NCT07076407 ·
Phase: Phase 3 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Methuen, Watertown, Worcester
-
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
NCT06223880 ·
Phase: Phase 4 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Accelerated TMS for Perinatal Depression
NCT06968390 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 55 Years ·
Sex: Female
· Massachusetts: Boston
-
Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression
NCT05630963 ·
Phase: Not specified ·
Ages: 18 Years to 45 Years ·
Sex: All (male and female)
· Massachusetts: Belmont
-
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
NCT05450432 ·
Phase: Phase 4 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06966401 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Watertown
-
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06911112 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston
-
Neural Correlates of Stress and Perceived Control in Adolescent Depression
NCT04788524 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 18 Years ·
Sex: Female
· Massachusetts: Belmont
-
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
NCT05570812 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Peripheral Neuroimmune Mechanisms of Hyperthermia
NCT05366270 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
NCT06376734 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Stress Dynamics and Familial Risk for Depression in Female Adolescents
NCT06816329 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 13 Years to 15 Years ·
Sex: Female
· Massachusetts: Belmont
-
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
NCT06633016 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Watertown
-
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
NCT05850689 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Methuen
-
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NCT06786624 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Watertown
-
Targeting Specific Brain Networks to Treat Specific Symptoms in Depression
NCT05523817 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder
NCT06247839 ·
Phase: Phase 3 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Massachusetts: Charlestown
-
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
NCT04296604 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33
NCT05573074 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Massachusetts: Boston
-
Triage Survey for Psychiatry Research Eligibility
NCT05800925 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Massachusetts: Boston, Watertown
-
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
NCT06547489 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Massachusetts: Boston, Russells Mills