Clinical trials recruiting for Portal Hypertension

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• 3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension
  NCT05475015 · Phase: Not specified · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension
  NCT07080697 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis
  NCT07521332 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Austrian PBC Registry
  NCT07598669 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 11 locations
• Austrian Registry on Transjugular Intrahepatic Portosystemic Shunts
  NCT03409263 · Phase: Not specified · Ages: 18 Years to 99 Years · Sex: All (male and female) · 1 location
• Cera™ Vascular Plug System Post-Market Clinical Follow-Up
  NCT06099015 · Phase: Not specified · Ages: 18 Years to 85 Years · Sex: All (male and female) · 9 locations
• Coil-Assisted Small-Diameter Covered-Stent Shunt Reduction for Refractory Hepatic Encephalopathy After TIPS
  NCT07799948 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Construction of a Portal Hypertension Biobank
  NCT07419724 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Direct Portal Pressure Measurement Via Endoscopic Ultrasound in Advanced Chronic Liver Disease (EVADIPP)
  NCT06266260 · Phase: Not specified · Ages: 18 Years to 99 Years · Sex: All (male and female) · 1 location
• EUS Guided Portal-systemic Pressure Gradient Measurement
  NCT04633356 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• EUS-guided Portal Pressure Gradient (PPG) Measurement: a Potential Alternative to the Traditional HVPG
  NCT06863012 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 85 Years · Sex: All (male and female) · 1 location
• Early TIPS in Patients With Liver Cirrhosis and Ascites
  NCT06576934 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Effect of Handgrip Strength on Portal Vein Hemodynamics in Patients With Liver Cirrhosis
  NCT07116096 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transplantation
  NCT07304466 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement
  NCT07439939 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Freiburg TIPS Registry
  NCT05782556 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Hepatic Venous Pressure Gradient Versus Endoscopic Ultrasound-Guided Portal Pressure Gradient - Comparative Analysis (HEPCA)
  NCT07424963 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 2 locations
• Improve the Strategies of Endoscopic and Interventional Treatment of Gastroesophageal Hemorrhage in Portal Hypertension
  NCT06970509 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 10 locations
• Non-Invasive Portal and Hepatic Vein Pressure Estimation
  NCT06210178 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Non-invasive Evaluation Program for TIPS and Follow Up Network 2 (NEPTUN2)
  NCT04393519 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Non-selective Beta-blocker in Compensated Advanced Chronic Liver Disease
  NCT06449339 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Noninvasive Prediction of Portal Hypertension in Cirrhosis Using Sound Touch Viscoelastography
  NCT06316869 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal
  NCT05470205 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease
  NCT04578301 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose
  NCT04073290 · Phase: Phase 4 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 6 locations
• Relevance of Sarcopenia in Advanced Liver Disease
  NCT05502198 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury
  NCT06173947 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors
  NCT06549673 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 8 locations
• TIPS for Complicated Portal Hypertension Related to Porto-Sinusoidal Vascular Disease
  NCT07163689 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis Patients
  NCT05325437 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Treatment Outcomes for Portal Hypertension Esophageal and Gastric Varices
  NCT07358663 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension
  NCT06797193 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• VICIS - Vienna Cirrhosis Study
  NCT03267615 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis
  NCT06265272 · Phase: Not specified · Ages: 18 Years to 99 Years · Sex: All (male and female) · 1 location
• hepatomiR cACLD Study
  NCT06432582 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Portal Hypertension often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Portal Hypertension trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.