Clinical trials recruiting for Prediabetes

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
  NCT06112418 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years and older · Sex: All (male and female) · 125 locations
• Acupuncture for Prediabetes With Combined Obesity
  NCT06359418 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 64 Years · Sex: All (male and female) · 1 location
• Behavioral Approach for Latinas Addressing Nutrition, Cravings, and Eating Patterns to Prevent Type 2 Diabetes
  NCT07478263 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: Female · 1 location
• Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
  NCT06055036 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Male · 1 location
• Blood Markers of Early Pancreas Cancer
  NCT03568630 · Phase: Not specified · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Butyrate-enriched Triglyceride and Diabetes Prevention
  NCT06384313 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 70 Years · Sex: All (male and female) · 1 location
• CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes
  NCT07140848 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being
  NCT07536256 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 25 Years · Sex: All (male and female) · 1 location
• Continuous Glucose Monitoring for Glucose and Weight Management in Prediabetes and Non-severe Type 2 Diabetes: A Prospective Community-based (Workplace) Cohort Study
  NCT06542627 · Phase: Not applicable (e.g. observational or device study) · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Crocus Sativus Tepals Water Extract in Obesity and Prediabetes
  NCT07261475 · Phase: Early Phase 1 · Ages: 40 Years to 65 Years · Sex: All (male and female) · 1 location
• Development of Smart Food /Nutraceutical Solutions Dedicated to Cardiometabolic Disorders in Ageing
  NCT07817290 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years and older · Sex: All (male and female) · 1 location
• Dinner Time for Obesity and Prediabetes
  NCT05745441 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 50 Years · Sex: All (male and female) · 2 locations
• Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients
  NCT06893913 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 55 Years · Sex: All (male and female) · 1 location
• Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
  NCT06424106 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 65 Years · Sex: All (male and female) · 1 location
• Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial
  NCT06365723 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 64 Years · Sex: All (male and female) · 3 locations
• Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
  NCT06897982 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 99 Years · Sex: All (male and female) · 1 location
• Food as Medicine for HIV and Diabetes
  NCT05026723 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Genetics of the Acute Response to Oral Semaglutide
  NCT05340868 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Glucose Variability and Cognition in Prediabetes
  NCT04201600 · Phase: Not specified · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
  NCT07743021 · Phase: Not specified · Ages: 40 Years and older · Sex: All (male and female) · 33 locations
• How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes
  NCT06817252 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 80 Years · Sex: All (male and female) · 2 locations
• Human Immunodeficiency Virus (HIV) Food Insecurities
  NCT04943861 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Insulin and Insulin Pulses During Fasting
  NCT06424015 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 65 Years · Sex: All (male and female) · 1 location
• Ketogenic Diet and Diabetes Demonstration Project
  NCT06115265 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Kuwait Adult Diabetes Epidemiological Multidisciplinary (KADEM) Program
  NCT06115876 · Phase: Not specified · Ages: 21 Years to 75 Years · Sex: All (male and female) · 1 location
• Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
  NCT05165706 · Phase: Not applicable (e.g. observational or device study) · Ages: 35 Years to 65 Years · Sex: All (male and female) · 1 location
• MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity
  NCT07505745 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
  NCT05799222 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources
  NCT05681468 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes
  NCT07120334 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years to 65 Years · Sex: All (male and female) · 1 location
• Multidisciplinary Care for Lifestyle Change for Metabolic Control and Quality of Life in Prediabetes (PreCPro)
  NCT06468553 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans
  NCT07450118 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• New T-UP: Engaging Vulnerable Students in Diabetes Prevention
  NCT07225218 · Phase: Not applicable (e.g. observational or device study) · Ages: 17 Years to 25 Years · Sex: All (male and female) · 1 location
• Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
  NCT07106879 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Peanuts for Cardiometabolic, Brain, and Intestinal Health
  NCT06867198 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 59 Years · Sex: All (male and female) · 1 location
• Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food
  NCT06988462 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Polish Registry of Diabetes (PolReD)
  NCT04657367 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Post Prandial Individual Responses to Different Foods
  NCT06989164 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes
  NCT07171281 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Sex, Psychopharmacology, and Diabetes
  NCT05951660 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Smartwatch-based Intervention for Cardiovascular Health (SWITCH)
  NCT07372729 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Social Determinants and a Diabetes Prevention Program Tailored for African Americans
  NCT05301413 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
  NCT06116149 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 1 location
• The Bialystok Bariatric Surgery Study
  NCT04634591 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Effect of Time-Restricted Eating in Cardiometabolic Health
  NCT05866406 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 75 Years · Sex: All (male and female) · 1 location
• The Sunnybrook Type 2 Diabetes Study
  NCT04455867 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
  NCT07804680 · Phase: Not specified · Ages: 6 Years to 18 Years · Sex: All (male and female) · 1 location
• Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
  NCT06412536 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
  NCT06007404 · Phase: Not specified · Ages: 14 Years to 18 Years · Sex: All (male and female) · 1 location
• Vitamin D and Type 2 Diabetes - Treat-To-Target
  NCT07448974 · Phase: Phase 3 · Ages: 30 Years to 74 Years · Sex: All (male and female) · 1 location
• WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time
  NCT06963736 · Phase: Not applicable (e.g. observational or device study) · Ages: 26 Years and older · Sex: All (male and female) · 1 location
• WeArable teChnology daTa driVen digitAl healTh cOachINg (ACTIVATION)- A Mixed-methods Study
  NCT06752772 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 75 Years · Sex: All (male and female) · 3 locations
• Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes
  NCT06482944 · Phase: Not applicable (e.g. observational or device study) · Ages: 6 Years to 59 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Prediabetes often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Prediabetes trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.