Clinical trials recruiting for Insulin Resistance

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents
  NCT07223151 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 18 Years · Sex: All (male and female) · 3 locations
• ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
  NCT07102797 · Phase: Not applicable (e.g. observational or device study) · Ages: 8 Years and older · Sex: Female · 1 location
• Acupuncture or Metformin for Insulin Resistance in Women With PCOS
  NCT02647827 · Phase: Phase 2 · Ages: 18 Years to 40 Years · Sex: Female · 2 locations
• Alpelisib Challenge Test (ACT)
  NCT07778524 · Phase: Phase 1 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Alternative Physical Activity Strategies for Breast Cancer Survivors
  NCT06633380 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: Female · 2 locations
• Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
  NCT05277558 · Phase: Not specified · Ages: 12 Years to 17 Years · Sex: All (male and female) · 2 locations
• Cardiometabolic Disease and Substrate Metabolism
  NCT07565727 · Phase: Not specified · Ages: 18 Years to 45 Years · Sex: Female · 1 location
• Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
  NCT03875625 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Characteristics of Papez Loop Neural Network in T2DM （Type 2 Diabetes Mellitus）
  NCT06912321 · Phase: Not specified · Ages: 45 Years to 70 Years · Sex: All (male and female) · 1 location
• Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes
  NCT05543083 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 17 Years · Sex: Female · 2 locations
• Collection of Human Metabolic Tissues
  NCT02861781 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• DIabetes GLycemic Assessment in Newly Confirmed Episodes
  NCT07690163 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
  NCT05950282 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Dietary Strategies for Remission of Type 2 Diabetes
  NCT04943926 · Phase: Not applicable (e.g. observational or device study) · Ages: 24 Years to 70 Years · Sex: All (male and female) · 1 location
• Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
  NCT06138821 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness
  NCT06487832 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Effect of Insulin Lowering on Lipogenesis
  NCT07403604 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Effect of Interval Aerobic Training and Mindfulness Breathing on Hormonal, Metabolic, and Tumor Markers in Postmenopausal
  NCT04471506 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 65 Years · Sex: Female · 1 location
• Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)
  NCT07297290 · Phase: Phase 3 · Ages: 20 Years to 59 Years · Sex: All (male and female) · 2 locations
• Effect of Timed-Restricted Eating on Metabolic Health
  NCT06061042 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 75 Years · Sex: All (male and female) · 1 location
• Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
  NCT06129110 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Effects of Antipsychotics on Brain Insulin Action in Females
  NCT06251635 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 35 Years · Sex: Female · 1 location
• Effects of Cranberry on Gut and Metabolic Health
  NCT07460856 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 70 Years · Sex: All (male and female) · 1 location
• Effects of Ketone Bodies on Insulin Sensitivity
  NCT07359625 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 70 Years · Sex: All (male and female) · 1 location
• Effects of Oral Glutamine Supplementation on Insulin Resistance and Functional Intestinal Disorders in Obese Patients.
  NCT04883515 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity
  NCT06847373 · Phase: Not applicable (e.g. observational or device study) · Ages: 10 Years to 18 Years · Sex: All (male and female) · 1 location
• Electro-Acupuncture for Obese Patients With Insulin Resistance
  NCT06609200 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 65 Years · Sex: All (male and female) · 1 location
• Exercise Effects on Adipose Tissue Structure and Function
  NCT04812314 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• Exercise Training on Brain Insulin Responsiveness
  NCT06039787 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 65 Years · Sex: All (male and female) · 1 location
• Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance
  NCT04578652 · Phase: Phase 3 · Ages: 12 Years to 18 Years · Sex: All (male and female) · 1 location
• Glucose Profiles in Women With Polycystic Ovary Syndrome
  NCT07483723 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 1 location
• Graded Insulin Suppression Test P&F
  NCT06592261 · Phase: Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Human Models of Selective Insulin Resistance: Alpelisib, Part I
  NCT06354088 · Phase: Phase 1 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Improving Glycemic Control With Electrical Stimulation
  NCT03947697 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Kodo Millet Porridge and Its Effects on Gut Health and Metabolic Syndrome
  NCT07703371 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 60 Years · Sex: All (male and female) · 1 location
• Leipzig Adipose Tissue Childhood Cohort
  NCT02208141 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
  NCT05165706 · Phase: Not applicable (e.g. observational or device study) · Ages: 35 Years to 65 Years · Sex: All (male and female) · 1 location
• MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity
  NCT07505745 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Metabolic Adaptations to Weight Loss With and Without Exercise
  NCT05806801 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• Metabolic Effects of Angiotensin-(1-7)
  NCT02646475 · Phase: Phase 1 · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI
  NCT05046483 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Metabolic and Bone Changes After Adjuvant Cancer Treatments in Early Non-metastatic Breast Cancer
  NCT03784651 · Phase: Not specified · Ages: 50 Years to 70 Years · Sex: Female · 1 location
• Mitigating the Pro-inflammatory Phenotype of Obesity
  NCT04934228 · Phase: Phase 1 · Ages: 18 Years to 79 Years · Sex: All (male and female) · 1 location
• Mitochondrial Substrate Utilization in the Diabetic Human Heart
  NCT05958706 · Phase: Not specified · Ages: 20 Years to 85 Years · Sex: All (male and female) · 1 location
• Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism
  NCT06722391 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• New Mechanisms of Obesity
  NCT06768827 · Phase: Not applicable (e.g. observational or device study) · Ages: 15 Years to 22 Years · Sex: All (male and female) · 1 location
• Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2
  NCT05833217 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 2 locations
• Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study
  NCT03742011 · Phase: Not specified · Ages: Up to 18 Years · Sex: All (male and female) · 1 location
• PREdiabetes GLycemic Impact and Data Evaluation
  NCT07599072 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
  NCT06167135 · Phase: Not specified · Ages: 20 Years to 45 Years · Sex: Female · 1 location
• Prebiotic Inulin for Late-Reproductive Individuals
  NCT07724522 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 55 Years · Sex: Female · 1 location
• Reversal of Lipid-Induced Insulin Resistance
  NCT02193295 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 90 Years · Sex: All (male and female) · 2 locations
• Small Extracellular Vesicles and Insulin Action
  NCT05933707 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 55 Years · Sex: All (male and female) · 1 location
• Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
  NCT04984226 · Phase: Phase 2 · Ages: 21 Years to 85 Years · Sex: All (male and female) · 2 locations
• Study of the Effect of Innate on the Inflammatory Response to Endotoxin
  NCT01143480 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• The Acute T-Rex (Timing of Resistance Exercise) Study
  NCT06366399 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 74 Years · Sex: All (male and female) · 2 locations
• The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV
  NCT07226128 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults
  NCT05912348 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 30 Years · Sex: All (male and female) · 1 location
• The Muscle Monitor: Early Skeletal Muscle Indicators of Insulin Resistance and Cardiometabolic Risk
  NCT07678736 · Phase: Not specified · Ages: 20 Years to 30 Years · Sex: All (male and female) · 1 location
• Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise
  NCT06959043 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 70 Years · Sex: All (male and female) · 1 location
• Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
  NCT06007404 · Phase: Not specified · Ages: 14 Years to 18 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Insulin Resistance often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Insulin Resistance trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.