Clinical trials recruiting for Primary Open Angle Glaucoma

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Phase II Trial of G01 Eye Drops for Glaucomatous Optic Neuropathy
  NCT07777861 · Phase: Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 9 locations
• A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients
  NCT07076303 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
  NCT06822738 · Phase: Phase 3 · Ages: 45 Years and older · Sex: All (male and female) · 27 locations
• Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues
  NCT07599241 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years to 75 Years · Sex: Female · 1 location
• Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma
  NCT05264818 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma
  NCT05564091 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years and older · Sex: All (male and female) · 4 locations
• Clinical Study Evaluating the Safety and Performance of the MIST Device for Intraocular Pressure Reduction in Patients With Primary Open-Angle Glaucoma
  NCT07358650 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 5 locations
• DSLT for Reducing Medication in Glaucoma
  NCT07390890 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Diagnostic Innovations in Glaucoma Study
  NCT00221897 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea
  NCT07447011 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years to 50 Years · Sex: All (male and female) · 2 locations
• Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults
  NCT04396002 · Phase: Not specified · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Hydrus® Microstent New Enrollment Post-Approval Study
  NCT04553523 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years and older · Sex: All (male and female) · 22 locations
• Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression
  NCT05940623 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Multicenter Glaucoma Study Investigating Standalone Canaloplasty
  NCT05786196 · Phase: Not applicable (e.g. observational or device study) · Ages: 22 Years and older · Sex: All (male and female) · 5 locations
• Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial
  NCT05844384 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma
  NCT06991270 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years and older · Sex: All (male and female) · 1 location
• PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group
  NCT07235592 · Phase: Not specified · Ages: 18 Years to 85 Years · Sex: All (male and female) · 11 locations
• Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study
  NCT03921931 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy
  NCT06313749 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma
  NCT06682962 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• XEN Glaucoma Gel Stent Versus Trabeculectomy
  NCT05439161 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Primary Open Angle Glaucoma often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Primary Open Angle Glaucoma trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.