Clinical trials recruiting for Glaucoma

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

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Recruiting trials

• "My Eyes, My Light": Amar Chokh, Amar Alo
  NCT07135570 · Phase: Not specified · Ages: 35 Years and older · Sex: All (male and female) · 1 location
• A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients
  NCT07076303 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma
  NCT07009236 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years and older · Sex: All (male and female) · 5 locations
• A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma
  NCT06792422 · Phase: Phase 4 · Ages: 45 Years and older · Sex: All (male and female) · 1 location
• A Trial of Hydrus Microstent Versus Goniotomy
  NCT06289491 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• Advancing Pediatric Retinal Imaging With Auto-aligned OCT
  NCT06841575 · Phase: Not applicable (e.g. observational or device study) · Ages: 1 Month and older · Sex: All (male and female) · 1 location
• Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years
  NCT07460791 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition
  NCT07364929 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 75 Years · Sex: All (male and female) · 2 locations
• Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma
  NCT05264818 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma
  NCT07119580 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Automated Applanation Tonometry - Updated
  NCT07298356 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Barcelona Esquerra Glaucoma Artificial Intelligence-based Screening Program (BEGAS)
  NCT06353542 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use
  NCT07217678 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
  NCT06492538 · Phase: Not specified · Ages: 30 Years to 85 Years · Sex: All (male and female) · 1 location
• Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
  NCT07341763 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Change in IOP Fluctuation After DSLT
  NCT07428668 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Choroidal and Retinal Features in PACD and POAG on OCT and OCTA
  NCT07580014 · Phase: Not specified · Ages: 18 Years to 90 Years · Sex: All (male and female) · 1 location
• Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression
  NCT05801471 · Phase: Not specified · Ages: 40 Years to 90 Years · Sex: All (male and female) · 2 locations
• Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical Hypotensors
  NCT06017362 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Community Based Treatment for (ComBaT) Glaucoma
  NCT06124521 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 2 locations
• Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment
  NCT06243497 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices
  NCT05523622 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients
  NCT06991712 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cross-modal Neuromodulation to Improve Balance and Cognition in Older Adults With Glaucoma: A Randomized Trial of Cerebellar Transcranial Electrical Stimulation
  NCT07771699 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years and older · Sex: All (male and female) · 1 location
• Data Gathering for A10900
  NCT07149740 · Phase: Not specified · Ages: 22 Years and older · Sex: All (male and female) · 4 locations
• Defining Retinal Structures Using Hyperspectral Retinal Imaging
  NCT07555574 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice
  NCT07015034 · Phase: Not applicable (e.g. observational or device study) · Ages: 70 Years and older · Sex: All (male and female) · 2 locations
• Dresden Glaucoma and Treatment Study (DGTS)
  NCT02959242 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells
  NCT04957329 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma
  NCT07354009 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 90 Years · Sex: All (male and female) · 1 location
• Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma Surgery
  NCT06760169 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Efficacy of Biofeedback Training for Glaucoma
  NCT07409077 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Efficacy of Direct Selective Laser Trabeculoplasty in Clinical Practice in Patients with Glaucoma
  NCT06808633 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Electrical Stimulation for Vision Neuroenhancement in Glaucoma
  NCT06685211 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Electrical Stimulation for the Treatment of Optic Neuropathies
  NCT05626426 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma
  NCT07209410 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma
  NCT07322965 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 75 Years · Sex: All (male and female) · 2 locations
• Evaluation of Different Perimetric Grids to Detect Central Visual Field Defect in Glaucoma Patients With Reduce Ganglion Cell Layer Thickness Measured by Spectral Domain OCT.
  NCT06227611 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery
  NCT06844292 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer
  NCT02014389 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
  NCT07218783 · Phase: Phase 3 · Ages: 22 Years and older · Sex: All (male and female) · 1 location
• Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
  NCT07218796 · Phase: Phase 3 · Ages: 22 Years and older · Sex: All (male and female) · 1 location
• Functional and Structural Imaging for Glaucoma
  NCT01957267 · Phase: Not specified · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
  NCT05924477 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 8 locations
• Glaucoma Laser Assessment of Stability and Sustainability
  NCT06963684 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using Combined Perceptual Learning and Transcranial Electrical Stimulation for Vision Enhancement
  NCT05874258 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE
  NCT06000865 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 80 Years · Sex: All (male and female) · 1 location
• Glaucoma Related Quality of Life
  NCT07510087 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Glaucoma Screening Using Artificial Intelligence Assisted Clinical Model in Singapore's Diabetic Eye Screening Program
  NCT07243665 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• Glaucoma Screening to Enhance At-Risk Californians' Health
  NCT06854198 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 2 locations
• Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma
  NCT06057051 · Phase: Not applicable (e.g. observational or device study) · Ages: 35 Years and older · Sex: All (male and female) · 1 location
• High Resolution, High-speed Multimodal Ophthalmic Imaging
  NCT04129021 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Hyperbaric Oxygen Therapy for Optic Neuropathies
  NCT06128720 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension
  NCT07588152 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression
  NCT05940623 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers
  NCT06629649 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial
  NCT07755761 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry
  NCT04024293 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma
  NCT03423758 · Phase: Not specified · Ages: 21 Years to 105 Years · Sex: All (male and female) · 1 location
• Is There a Response of Glaucoma to Baduanjin Exercise in Elders?
  NCT07163676 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years to 75 Years · Sex: All (male and female) · 1 location
• Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management
  NCT07780916 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) Shunt
  NCT06691555 · Phase: Not specified · Ages: 40 Years to 90 Years · Sex: All (male and female) · 1 location
• Low Intraocular Pressure Cataract Surgery With Zeiss Quatera in Glaucoma Patients
  NCT06712758 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Magnetic Resonance Imaging of Cerebral Connectivity and Volume in Neurodegeneration and Glaucoma
  NCT07802769 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Metformin as a Neuroprotective Therapy for Glaucoma
  NCT05426044 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2
  NCT06934577 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Modified Trabeculectomy After Failure of Combined Phaco With GATT
  NCT07455786 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 70 Years · Sex: All (male and female) · 1 location
• NorMIGS - a Study of Micro-invasive Glaucoma Surgery
  NCT05340647 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Novel Glaucoma Diagnostics
  NCT00286637 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Optic Nerve Head Strain in Non-glaucoma Subjects
  NCT07425535 · Phase: Early Phase 1 · Ages: 30 Years to 90 Years · Sex: All (male and female) · 1 location
• Optimal Non-invasive Brain Stimulation for Peripheral Vision
  NCT04846140 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Optimize Pediatric OCT Imaging
  NCT06139523 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Perimetric Testing With Virtual Reality
  NCT06549010 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 70 Years · Sex: All (male and female) · 1 location
• Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
  NCT07075718 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Pilocarpine Use After Kahook Goniotomy
  NCT03933631 · Phase: Phase 3 · Ages: 30 Years to 100 Years · Sex: All (male and female) · 2 locations
• Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies
  NCT07145073 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Retinal Blood Flow and Autoregulation
  NCT05344274 · Phase: Phase 4 · Ages: 18 Years to 88 Years · Sex: All (male and female) · 4 locations
• Rocklatan vs Latanoprost Post-DSLT
  NCT07465913 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery
  NCT07036510 · Phase: Phase 1, Phase 2 · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• Stem Cell Ophthalmology Treatment Study II
  NCT03011541 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Strategies for Improving Linkage-to-Care After Eye Disease Screening
  NCT06943599 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy
  NCT06993597 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma
  NCT06274593 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• The Glaucoma Nicotinamide Trial
  NCT05275738 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• The Glaucoma and Retinopathy Screening Study
  NCT06882356 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 7 locations
• The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis
  NCT04232982 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• This Study Examines Whether Personality Traits Influence the Frequency or Severity of Ocular Adverse Effects Reported by Patients Using Glaucoma Medications. The Findings May Identify Patients at Greater Risk of Intolerance and Support More Personalized Treatment and Counselling.
  NCT07739784 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.
  NCT07425496 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Topical Insulin for Glaucoma
  NCT05206877 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma
  NCT06682962 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting
  NCT05694858 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications
  NCT04354545 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
  NCT07495852 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Validation of the Artificial Intelligence Subsystem of the DDART Medical Device for the Automated Detection of Lesions Compatible With Glaucoma in a Random Sample of Retinal Fundus Photographs
  NCT07758569 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Village-Integrated Eye Worker Trial II
  NCT03752840 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• World Sight Foundation Field Machine (WSFFM) Pilot
  NCT07674069 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 99 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Glaucoma often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Glaucoma trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.