Phase 3 Sickle cell disease trials recruiting now

All Sickle cell disease trials, every phase

Other phases for Sickle cell disease

Phase 3 Sickle cell disease trials

• A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
  NCT05431088 · Phase: Phase 2, Phase 3 · Ages: 12 Years and older · Sex: All (male and female) · 80 locations
• A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
  NCT06609226 · Phase: Phase 3 · Ages: 2 Years and older · Sex: All (male and female) · 106 locations
• A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
  NCT06612268 · Phase: Phase 3 · Ages: 12 Years and older · Sex: All (male and female) · 175 locations
• A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)
  NCT07656415 · Phase: Phase 3 · Ages: 12 Years and older · Sex: All (male and female) · 3 locations
• A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
  NCT06439082 · Phase: Phase 3 · Ages: 12 Years to 100 Years · Sex: All (male and female) · 35 locations
• Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease
  NCT06818266 · Phase: Phase 3 · Ages: 2 Years and older · Sex: All (male and female) · 1 location
• Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
  NCT05477563 · Phase: Phase 3 · Ages: 12 Years to 35 Years · Sex: All (male and female) · 6 locations
• Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease
  NCT07274254 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 12 locations
• Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia
  NCT06761560 · Phase: Phase 2, Phase 3 · Ages: 6 Months to 18 Years · Sex: All (male and female) · 1 location
• Oral Ketamine for Treatment of Vaso-Occlusive Pain
  NCT05378555 · Phase: Phase 3 · Ages: 12 Years to 24 Years · Sex: All (male and female) · 1 location
• Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa
  NCT05285917 · Phase: Phase 3 · Ages: 6 Months to 12 Years · Sex: All (male and female) · 1 location
• RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease
  NCT05392894 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease
  NCT07247188 · Phase: Phase 3 · Ages: 2 Years to 17 Years · Sex: All (male and female) · 7 locations
• The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
  NCT06975865 · Phase: Phase 3 · Ages: 10 Years to 65 Years · Sex: All (male and female) · 53 locations

Common questions

What does Phase 3 mean?

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Is this list complete?

No. For the full record, search ClinicalTrials.gov.