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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
NCT06587828 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Orange, Sherman Oaks
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A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT06405087 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· California: Loma Linda, Orange, Palo Alto
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A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07185009 ·
Phase: Phase 3 ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· California: Coronado, Murrieta, Victorville
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A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
NCT04844606 ·
Phase: Phase 3 ·
Ages: 2 Years to 19 Years ·
Sex: All (male and female)
· California: San Francisco
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
NCT07483073 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Los Angeles, Oxnard
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A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
NCT07196748 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· California: Anaheim, Coronado, Lancaster, Los Angeles
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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
NCT05076175 ·
Phase: Phase 2, Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· California: Garden Grove, Loma Linda, Los Angeles, Palo Alto
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A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
NCT06598943 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Chula Vista, Coronado, Garden Grove, Lancaster
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07577856 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Anaheim, Chula Vista, Los Alamitos, San Diego
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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
NCT07012395 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Canoga Park, La Jolla, Lancaster
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A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
NCT06095128 ·
Phase: Phase 4 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· California: Los Angeles, Newport Beach
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A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
NCT06581328 ·
Phase: Phase 4 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Escondido, Murrieta, Newport Beach, Orange
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567 ·
Phase: Phase 3 ·
Ages: 2 Years and older ·
Sex: All (male and female)
· California: Los Angeles, San Diego, San Francisco
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A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
NCT06100289 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· California: Loma Linda, Orange, Palo Alto
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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06588855 ·
Phase: Phase 3 ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· California: Apple Valley, Garden Grove, Lancaster, Los Angeles
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A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
NCT07463183 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Anaheim, Coronado
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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
NCT05287126 ·
Phase: Phase 2 ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· California: Garden Grove, Loma Linda, San Bernardino, San Francisco
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A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
NCT06979336 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Lancaster, San Diego
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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis
NCT06975722 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Escondido, Lancaster, Thousand Oaks
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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
NCT07071519 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· California: San Diego, San Francisco
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An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis
NCT07665723 ·
Phase: Phase 1 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· California: Chula Vista
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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07184996 ·
Phase: Phase 3 ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· California: Arcadia, Canoga Park, Coronado, Folsom
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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis
NCT06398626 ·
Phase: Not specified ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· California: La Jolla, Los Alamitos
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BOOM-IBD2 Pivotal Clinical Trial
NCT06571669 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· California: Folsom, Los Angeles, Newport Beach, Palo Alto
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Effects of Pomegranate Juice on Ulcerative Colitis
NCT07115862 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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Fermented Food-Supplemented Diet in Ulcerative Colitis
NCT04401605 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto
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Functional Outcomes in Ulcerative Colitis Patients With Ileal Pouch Anal Anastomosis Treated With High Intensity Focused Electromagnetic Stimulation
NCT07034443 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Los Angeles
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Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)
NCT05987852 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· California: Los Angeles
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Impact of Prebiotics in Ulcerative Colitis
NCT06495658 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· California: Los Angeles
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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
NCT07186101 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Anaheim, Lancaster, Los Angeles
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LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Anaheim, Folsom, Temple City, Victorville
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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
NCT06937086 ·
Phase: Phase 3 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: Anaheim, Beverly Hills, Los Alamitos, Northridge
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Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
NCT04721873 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: La Jolla
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R-3750 in Patients With Mild to Moderate Ulcerative Colitis
NCT05666960 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· California: Valencia
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Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
NCT07697456 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Anaheim, Lancaster, Los Alamitos, Rialto
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Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06029972 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Chula Vista, Coronado, Garden Grove, La Jolla
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Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
NCT06619990 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Palo Alto
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Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis
NCT07686081 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Chula Vista
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Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
NCT04314375 ·
Phase: Phase 4 ·
Ages: 5 Years to 17 Years ·
Sex: All (male and female)
· California: Garden Grove
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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
NCT03816345 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto, Sacramento
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The Influence of a Fasting Mimicking Diet on Ulcerative Colitis
NCT03615690 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: Palo Alto
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The Use of Butyrate Therapy in Pediatric Ulcerative Colitis
NCT05218850 ·
Phase: Phase 2 ·
Ages: 7 Years to 21 Years ·
Sex: All (male and female)
· California: Los Angeles
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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
NCT05230173 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Irvine, La Jolla, Los Angeles, Palo Alto
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Understanding Ozanimod's MOA Via Mass Cytometry in Ulcerative Colitis
NCT06311123 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Diego