Clinical trials recruiting for Weight Loss

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
  NCT06776081 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• BrainWeighve App Feasibility Study
  NCT05530538 · Phase: Not applicable (e.g. observational or device study) · Ages: 14 Years to 21 Years · Sex: All (male and female) · 1 location
• Change in Body Weight and BMI in PWH with DOR/3TC/TDF Compared with INSTI
  NCT06602622 · Phase: Phase 4 · Ages: 18 Years to 80 Years · Sex: Male · 2 locations
• Changes in Taste and Eating Habits Associated With GLP-1 Agonists in Weight Loss Patients
  NCT07229170 · Phase: Not specified · Ages: 18 Years to 60 Years · Sex: All (male and female) · 4 locations
• Chinese Obesity and MEtabolic Surgery Database (COMES Database)
  NCT06275061 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• DUTCH Weight Control in Atrial Fibrillation Study
  NCT06184633 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
  NCT06138821 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure
  NCT06423599 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Effect of a Postbiotic Supplementation in Overweight and Obese Subjects: A Randomized Controlled Trial (PARABIOTICS-2).
  NCT07165431 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults
  NCT06811324 · Phase: Phase 2 · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
  NCT04494048 · Phase: Not specified · Ages: 18 Years to 89 Years · Sex: All (male and female) · 1 location
• Evaluating Anti-Obesity Medications 6 Months After Metabolic Surgery
  NCT07163650 · Phase: Phase 4 · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Exercise Effects on Adipose Tissue Structure and Function
  NCT04812314 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
  NCT06724406 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)
  NCT07144800 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Fasted vs. Fed State Exercise
  NCT07487090 · Phase: Phase 2 · Ages: 18 Years to 59 Years · Sex: All (male and female) · 1 location
• Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery
  NCT06226194 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Implant-based Breast Reconstruction in Post-bariatric Women - a Registry-based National Study
  NCT07059104 · Phase: Not specified · Ages: No age limits stated · Sex: Female · 1 location
• Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
  NCT07213466 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• International Weight Control Registry
  NCT04907396 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 7 locations
• Lifestyle Changes in Older Adults With Metabolic Syndrome and Tinnitus
  NCT06702085 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years to 75 Years · Sex: All (male and female) · 2 locations
• Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC
  NCT06998758 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Metabolic Adaptations to Weight Loss With and Without Exercise
  NCT05806801 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• Metabolic Effects of a Diet Replaced With Essential Amino Acids
  NCT06309563 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 65 Years · Sex: All (male and female) · 1 location
• Metabolic Health, Bones and Nuts During Weight Loss in Adults
  NCT06949280 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 75 Years · Sex: All (male and female) · 1 location
• Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity
  NCT06809166 · Phase: Phase 4 · Ages: 18 Years to 64 Years · Sex: All (male and female) · 9 locations
• Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
  NCT06967389 · Phase: Not specified · Ages: 12 Years to 17 Years · Sex: All (male and female) · 1 location
• Mobile Applet for Weight Management in Obese Heart Failure Patients
  NCT06455878 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 26 locations
• Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance
  NCT06785064 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Orbera365 Intragastric Balloon System (Abbreviated as'Orbera365')
  NCT07195708 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus
  NCT05798494 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 38 Years · Sex: All (male and female) · 1 location
• Pilot Project on Interdisciplinary Therapy of Obesity
  NCT01344525 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 3 locations
• Planning Grant for TOPS for Breast Cancer Survivors
  NCT06658912 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 90 Years · Sex: Female · 1 location
• Probiotic Intervention on Body Weight
  NCT06989177 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 50 Years · Sex: All (male and female) · 1 location
• Protein Supplementation Intervention on Body Weight
  NCT06989203 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 50 Years · Sex: All (male and female) · 1 location
• Testing a Tailored Approach to Long-Term Weight Loss Success
  NCT07577765 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• The Effect of Different Diets on Arterial Stiffness in Obese Patients on Semaglutide
  NCT04990024 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 49 Years · Sex: All (male and female) · 1 location
• The Impact of Lifestyle Intervention on Weight and Fertility in Obese Males
  NCT06339840 · Phase: Not applicable (e.g. observational or device study) · Ages: 22 Years to 40 Years · Sex: Male · 1 location
• The Role of Microbiome in Recurrent Obesity Before and After Antibiotic/Placebo Treatment
  NCT06681246 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Time Restricted Eating for WeIght LoSs MainTenance-2
  NCT07190170 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 65 Years · Sex: All (male and female) · 1 location
• WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
  NCT06861790 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 75 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Weight Loss often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Weight Loss trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.