How many clinical trials are studying Nicotinamide?

6 recruiting trials in our tracked data involve Nicotinamide.

What conditions is Nicotinamide being studied for?

In our tracked recruiting trials, Nicotinamide is being studied in trials for Glaucoma, Hypertension, Melanoma.

Yes. According to the FDA drug label available through openFDA, Nicotinamide is an FDA-approved drug.

Recruiting trials

Conditions studied

US states with sites

Countries

FDA-approved: Yes. Nicotinamide appears in the FDA drug-label database. Marketed as Nicotinamide.
Drug class: Copper-containing Intrauterine Device; Standardized Chemical Allergen (FDA established pharmacologic class)

Reason (FDA)	Classification	Status	Initiated
cGMP deviations — Blossom Pharmaceuticals	Class II (FDA: may cause temporary or reversible harm)	Ongoing	2025-10-31
Microbial Contamination of Non-Sterile Products: Elevated counts of gram positive rods were found during environmental testing — Faria Limited LLC dba Sheffield Pharmaceuticals	Class II (FDA: may cause temporary or reversible harm)	Terminated	2013-11-22
cGMP deviations — Blossom Pharmaceuticals	Class II (FDA: may cause temporary or reversible harm)	Ongoing	2025-10-31
CGMP Deviations — SYNCHRONICITY SPA INC, DBA SUNTE	Class II (FDA: may cause temporary or reversible harm)	Ongoing	2024-05-24
Microbial Contamination of Non-Sterile Products: Presence of Aspergillus Sydowii (Mold) — SYNCHRONICITY SPA INC, DBA SUNTE	Class I (FDA: reasonable probability of serious harm or death)	Ongoing	2024-05-24

Phase 1 1 Phase 2 3 Phase 3 1 Not applicable 1

Condition	Trials
Glaucoma	2
Hypertension	2
Melanoma	2
Carcinoma, Basal Cell	1
Carcinoma, Squamous Cell	1
Chronic Lymphocytic Leukemia	1
Fatty Liver	1
Hepatic Fibrosis	1
Keratinocyte Carcinoma	1
NAFLD	1
NASH	1
Nicotinamide	1
Non-melanoma Skin Cancer	1
Non-melanoma Skin Cancer (NMSC)	1
Obesity	1

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease
NCT04055818 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients
NCT06991712 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
NCT04844528 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
Nicotinamide Chemoprevention for Keratinocyte Carcinoma in Solid Organ Transplant Recipients - Pivotal Trial
NCT05955924 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 7 locations
Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB)
NCT06599918 · Phase: Phase 2 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 2 locations
The Glaucoma Nicotinamide Trial
NCT05275738 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations

Yes, marketed as Nicotinamide.

6 recruiting trials across 15 conditions.

No. For the full record, search ClinicalTrials.gov.