Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial
Recruiting · NCT05120492 · Interventional (participants receive a specific treatment) · Lead sponsor: Nova Scotia Health Authority
View the official record on ClinicalTrials.gov →Interventions studied
bariatric surgery followed by total knee replacement
What this trial is about
Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- severe knee osteoarthritis body-mass index of 45 to 60
Exclusion criteria
- previous total replacement of the same knee, a need for bilateral total knee replacement, and knee pain during the previous week that the patient rated at higher than 60 mm on a 100-mm visual-analogue scale. Also,prior bariatric or complex foregut surgery, significant cardiovascular, pulmonary, renal, liver, gastrointestinal, psychiatric disorders, pregnancy, malignancy within last 5 years, anemia, coagulopathy requiring anti-coagulation therapy.
Where it is running
1 location listed.
- Nova Scotia Health - Halifax, Nova Scotia, Canada