Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone
Recruiting · NCT05254730 · Interventional (participants receive a specific treatment) · Lead sponsor: Adrien Peyrache
View the official record on ClinicalTrials.gov →Interventions studied
macro-micro tetrodes for intracranial recording
What this trial is about
record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsy
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure
Exclusion criteria
- severe psychiatric disorders,
- severe agitation during their crisis
- contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system,
- contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women,
- anti thrombotic ongoing treatment.
Where it is running
1 location listed.
- McGill University - Montreal, Quebec, Canada