Biobank and Brain Health in Bordeaux.
Recruiting · NCT05322343 · Observational (researchers observe without assigning treatment) · Lead sponsor: University Hospital, Bordeaux
View the official record on ClinicalTrials.gov →Interventions studied
Fasting blood sampling.Hair and a tonenail (or hand nail) samplingMeasurementsMedical visitNasal microbiotaNeuroimagingQuestionnairesSaliva collection and nasal or nasopharyngeal swabUrine and stool samples
What this trial is about
B cube is a new generation cohort to study the determinants and natural history of brain aging, using molecular epidemiology, in a representative sample (N=2000) of the general population from the age of 55 (the approximate age of onset of the first cognitive disorders and a target population particularly receptive to prevention messages). Special interest will be given to nutrition, a promising environmental exposure for prevention.
Who can take part
Age range
55 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- For the main study:
- live in Bordeaux metropolitan area,
- be between 55 and 80 years old (included),
- selected in terms of socioeconomic level, according to a sampling strategy by age groups and income categories representative of the general population between 55 and 80 years of age
- be affiliated with the social security system,
- agree to take a blood sample for the biobank.
- For the MRI sub-study: be between 55 and 75 years old (included). Inclusion criteria for the immune response substudy: be 70 years of age or older or participate in the MRI study; agree to take a supplemental blood sample for this substudy.
Exclusion criteria
- For the main study: persons under guardianship (or more generally under protection), unable to give consent to participate.
- For the MRI sub-study: have a contraindication to MRI examination (pacemaker, a valve prosthesis or any other internal electrical/magnetic device; history of neurosurgery or aneurysm; claustrophobia; presence of metal fragments in the eyes, brain or spinal cord).
Where it is running
3 locations listed.
- University Hospital of Bordeaux - Bordeaux, Bordeaux, France
- University Hospital of Bordeaux - Bordeaux, Bordeaux, France
- University Hospital of Bordeaux - Bordeaux, Bordeaux, France