Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
Recruiting · NCT05493722 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Minnesota
View the official record on ClinicalTrials.gov →Interventions studied
PS and OS stimulation order 1PS and OS stimulation order 2PS and OS stimulation order 3
What this trial is about
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Early Phase 1
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- medically refractory epilepsy
- already have a deep brain stimulator in place
Exclusion criteria
- severe dementia at investigator discretion
Where it is running
1 location listed across 1 US state.
- University of Minnesota - Minneapolis, Minnesota, United States