Patient-driven Management of BP in CKD
Recruiting · NCT05546099 · Interventional (participants receive a specific treatment) · Lead sponsor: VA Office of Research and Development
View the official record on ClinicalTrials.gov →Interventions studied
Self-management of BP medicationsSelf-monitoring of home BP
What this trial is about
The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and the standard care. 60 Veterans with chronic kidney disease (CKD) will be included in the study. The study will further evaluate factors that may influence the Veteran to accept the self-management approach and what factors in the VHA healthcare system affect the implementation of the self-management approach.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 3
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age \>= 18 years,
- CKD stage 3 or 4 (estimated GFR: 15-59 mL/min/1.73m2) or
- Stage 2 CKD (estimated GFR 60-89 mL/min/1.73m2) with urinary albumin/creatinine ratio (ACR 300 mg/g if no DM and 30 mg/g if with DM), and
- Uncontrolled hypertension defined as the avg of 2 readings \> 140 systolic.
Exclusion criteria
- Severely uncontrolled hypertension defined as systolic BP \>180,
- Patients with resistant hypertension and taking 4 BP medications,
- Orthostatic hypotension defined as reduced systolic BP by 20 mmHg or diastolic BP by 10 mmHg after 3 minutes of standing,
- Severe CKD defined as estimated GFR \< 20 mL/min/1.73m2,
- Life expectancy \<1 year,
- Severe liver disease,
- Severe congestive heart failure,
- Severe cognitive decline due to dementia,
- Pregnant, breastfeeding, or unwilling to use adequate birth control
Where it is running
1 location listed across 1 US state.
- Iowa City VA Health Care System, Iowa City, IA - Iowa City, Iowa, United States