Clinical trials sponsored by VA Office of Research and Development

Phase breakdown

Conditions studied

Recruiting trials led by VA Office of Research and Development

• A Computerized Depression Intervention in Veterans
  NCT06217198 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A New Intervention to Improve Function in Veterans With Anxiety and Depression
  NCT06188923 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness
  NCT05537376 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
  NCT05593497 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Male · 9 locations
• A Study to Improve Skeletal Muscle in Veterans With HIV
  NCT06845046 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 80 Years · Sex: Male · 1 location
• Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
  NCT05491538 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans
  NCT06906185 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: Female · 1 location
• Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity
  NCT06745063 · Phase: Phase 2 · Ages: 30 Years to 60 Years · Sex: All (male and female) · 1 location
• Atomoxetine and Executive Function in PTSD
  NCT06573970 · Phase: Phase 4 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Auricular Neuromodulation in Veterans With Fibromyalgia
  NCT06415591 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
  NCT04877197 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC
  NCT06681220 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 11 locations
• Blood Flow Restriction And Veterans With MS
  NCT05433103 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients
  NCT04163614 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
  NCT05937854 · Phase: Phase 2 · Ages: 35 Years to 89 Years · Sex: All (male and female) · 5 locations
• Bright Light Therapy for OSA
  NCT05917119 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 65 Years · Sex: All (male and female) · 1 location
• CBT-CP for Veterans With SMI
  NCT06758414 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
  NCT05996328 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 16 locations
• CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
  NCT05931276 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 8 locations
• Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
  NCT04038502 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Male · 18 locations
• Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder
  NCT05858346 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Comparing the Safety and Efficacy of Apixaban and Rivaroxaban
  NCT06953726 · Phase: Phase 4 · Ages: 65 Years and older · Sex: All (male and female) · 5 locations
• Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)
  NCT04124029 · Phase: Not specified · Ages: 30 Years to 90 Years · Sex: All (male and female) · 1 location
• Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease
  NCT05400499 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Dosing rTMS for Depression Post-SCI
  NCT05553353 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Dynamic Treatment Regiments for Glucocorticoid Tapering
  NCT06072768 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• ERP to Improve Functioning in Veterans With OCD
  NCT05240924 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 19 locations
• EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer
  NCT05467748 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 5 locations
• Effects of Combination Exercise on Fatigability in Veterans With Chronic Kidney Disease
  NCT04397159 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 85 Years · Sex: All (male and female) · 1 location
• Empagliflozin Treatment in Kidney Transplant Recipients
  NCT06013865 · Phase: Phase 4 · Ages: 19 Years and older · Sex: All (male and female) · 5 locations
• Enhancing Rehabilitation for Veterans With Serious Mental Illness
  NCT06586164 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 83 Years · Sex: All (male and female) · 1 location
• Enhancing Veteran-Clinical Collaboration in VA PRRCs
  NCT06898879 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 6 locations
• Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer
  NCT06671613 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength
  NCT06607913 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years and older · Sex: All (male and female) · 2 locations
• Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
  NCT05157620 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Expanding Exercise Programming for Veterans Through Telehealth
  NCT05666167 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Expressive Writing on Minority Stressors Among Sexual Minority Veterans
  NCT05897021 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Feasibility and Safety of a Portable Exoskeleton to Improve Mobility in Parkinson's Disease
  NCT06028529 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 90 Years · Sex: All (male and female) · 1 location
• Health Promotion With Targeted Exercise Intervention for Decreasing Fall Risk and Inactivity in Aging Veterans With Obesity and Signs of Sarcopenia
  NCT07206368 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years and older · Sex: All (male and female) · 1 location
• High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
  NCT05011383 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Male · 17 locations
• Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
  NCT04179981 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0
  NCT07215572 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Inclined Versus Standard Exercise for COPD Patients
  NCT06749262 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 80 Years · Sex: All (male and female) · 1 location
• Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
  NCT05465044 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 8 locations
• Ketamine for Veterans With Parkinson's Disease
  NCT06231563 · Phase: Phase 2 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
  NCT06419439 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease
  NCT06405334 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI
  NCT06138054 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression
  NCT05220202 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years to 99 Years · Sex: All (male and female) · 2 locations
• Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
  NCT04419272 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints
  NCT05776056 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 3 locations
• Mobile Technology to Measure Knee Health in Osteoarthritis
  NCT07580222 · Phase: Not specified · Ages: 30 Years and older · Sex: All (male and female) · 1 location
• Mode of Exercise and Bone Biomarkers in Older Veterans
  NCT05266976 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease
  NCT06088355 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
  NCT05880108 · Phase: Not applicable (e.g. observational or device study) · Ages: Up to 80 Years · Sex: All (male and female) · 2 locations
• Multilevel Intervention for Precision Oncology
  NCT06825715 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Muscle Blood Flow Regulation in HFpEF
  NCT05115890 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• NAFLD Clinical Care Pathway
  NCT06671886 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
  NCT02703207 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years to 89 Years · Sex: All (male and female) · 1 location
• Neurophysiologic Biomarkers for Cognitive Rehabilitation
  NCT05945602 · Phase: Not specified · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Non-invasive VNS for Parkinson's Gait
  NCT06562569 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 88 Years · Sex: All (male and female) · 1 location
• Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder
  NCT06399653 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 65 Years · Sex: All (male and female) · 1 location
• Novel Approaches for Improving Vascular Function in Veterans With HFpEF
  NCT06312748 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease
  NCT06857851 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• PEP Buddy in Pulmonary Rehabilitation
  NCT07404826 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 89 Years · Sex: All (male and female) · 2 locations
• Patient-driven Management of BP in CKD
  NCT05546099 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Pharmacogenomic Informed Statin Prescribing
  NCT06568601 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 75 Years · Sex: All (male and female) · 2 locations
• Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis
  NCT04373317 · Phase: Phase 4 · Ages: 40 Years and older · Sex: All (male and female) · 24 locations
• Prediction Augmented Screening Initiative
  NCT06538636 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 4 locations
• Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
  NCT07226232 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 5 locations
• Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc
  NCT06084338 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Male · 4 locations
• Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans
  NCT06488144 · Phase: Phase 3 · Ages: 40 Years to 90 Years · Sex: All (male and female) · 5 locations
• Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
  NCT06574165 · Phase: Not applicable (e.g. observational or device study) · Ages: 19 Years to 85 Years · Sex: All (male and female) · 1 location
• Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
  NCT04982419 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Repositioning Immunotherapy in VetArans With Lung Cancer
  NCT06275360 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 7 locations
• Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
  NCT05994482 · Phase: Not specified · Ages: 75 Years and older · Sex: All (male and female) · 2 locations
• Targeted Telerehabilitation Following Curative Intent Therapy of Lung Cancer
  NCT05179408 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial
  NCT07010757 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
  NCT05254431 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
  NCT05701982 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 100 Years · Sex: All (male and female) · 1 location
• Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans
  NCT05526144 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
  NCT06162741 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 8 locations
• Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer
  NCT04787744 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: Male · 20 locations
• Weight Loss and ExeRcise for Post-stroke Veterans
  NCT06322030 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders
  NCT06204705 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• rTMS to Improve Cognition in Parkinson's
  NCT03836950 · Phase: Phase 1, Phase 2 · Ages: 50 Years and older · Sex: All (male and female) · 2 locations

Common questions

How many trials is VA Office of Research and Development recruiting for?

VA Office of Research and Development is the lead sponsor of 86 recruiting trials.

Is this list complete?

No. For the full record, search ClinicalTrials.gov.