Identifying and Characterizing Preclinical MS
Recruiting · NCT05787795 · Observational (researchers observe without assigning treatment) · Lead sponsor: Yale University
View the official record on ClinicalTrials.gov →Interventions studied
biological samples
What this trial is about
The purpose of this research study is to try and identify risk factors and biologic changes that suggest that someone may go on to develop multiple sclerosis before a person has shown any symptoms of the disease.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age 18+
- Having one or more risk factors for multiple sclerosis, including one or more of the below:
- Individuals known to have a radiologically isolated syndrome
- Individuals with a family history of multiple sclerosis (first degree family member)
- Individuals with personal risk factors, which are known to include smoking, obesity, Epstein Barr virus infections, Vitamin D deficiency, genetic risk score
Exclusion criteria
- Currently pregnant
- Diagnosis of multiple sclerosis or any ongoing, systemic autoimmune disease
- Ongoing treatment with immunosuppressive medications
Where it is running
1 location listed across 1 US state.
- Yale University - North Haven, Connecticut, United States