Stimulation-Induced Changes in Fronto-Limbic Network
Recruiting · NCT05854160 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Alabama at Birmingham
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The purpose of this research is to better understand how emotion processing unfolds in the brain using stereoelectroencephalography (sEEG) and direct brain stimulation. This study will use standard behavioral emotion processing tasks combined with neural recording and direct brain stimulation to assess different aspects of emotion processing. Stimulation pulses during pre and post-test periods will assess the effects of stimulation before and after conditioning, the results of which will be combined with results from the activity of each electrode during the emotion tasks to inform us of the nature of emotion processing in the brain and allow us to devise brain modulation protocols in the future.
Who can take part
Inclusion criteria
- 1\) implantation of sEEG electrodes for SOC epilepsy surgery evaluation
- 2\) cognitive ability to perform simple tasks and to understand instructions
- 3\) implanted electrodes in the amygdala and medial PFC regions
- 4\) competency to understand and sign a written informed consent.
Exclusion criteria
- 1\) an inability to complete the task
Where it is running
1 location listed across 1 US state.
- Epilepsy Monitoring Unit UAB Hospital - Birmingham, Alabama, United States