Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
Recruiting · NCT05885646 · Observational (researchers observe without assigning treatment) · Lead sponsor: University Hospital, Angers
View the official record on ClinicalTrials.gov →Interventions studied
Sulthiame
What this trial is about
The effect of sulthiame on EEG has been studied in epilepsy syndromes of childhood with sleep activation by comparing sleep EEG obtained at baseline and after 4 weeks of treatment. The aim of the study is to know if an effect is still identifiable after 2 weeks of treatment by performing sleep EEG recordings after 2 and 4 weeks of treatment, respectively.
Who can take part
Age range
6 Years to 15 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Diagnosis of epilepsy syndromes of childhood with sleep activation
- Failure of at least two anti-epileptic drugs (AED)
- Sleep EEG performed in the last 7 days before inclusion and showing interictal epileptiform discharges (baseline EEG)
Exclusion criteria
- Previous trial with sulthiame
- More than 2 AED at inclusion
- Use of corticosteroids at inclusion
- Change in the anti-epileptic treatment in the 7 days before baseline EEG
Where it is running
3 locations listed.
- Angers University Hospital, Pediatric department - Angers, France
- Strasbourg University Hospital, Pediatric department - Strasbourg, France
- Toulouse University Hospital, Pediatric Neurology Department - Toulouse, France