Cardiovascular Risk in Digital Osteoarthritis
Recruiting · NCT05923736 · Interventional (participants receive a specific treatment) · Lead sponsor: University Hospital, Clermont-Ferrand
View the official record on ClinicalTrials.gov →Interventions studied
EndoPAT™ 2000 systemIntima media thickness ultrasoundX-ray absorptiometry (DXA)hand ultrasound
What this trial is about
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and control group of patients with non-osteoarthritis disease paired by measurement of carotid intima-media thickness. All participants will undergo an ultrasound scan to measure carotid intima media thickness, a clinical assessment with the rheumatologist and a cardiovascular risk assessment.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- For all subjects:
- Adult male or female subject
- Able to give informed consent to participate in research
- Affiliated with a Social Security plan
- For the digital osteoarthritis group:
- Consultant in Rheumatology at Clermont-Ferrand University Hospital
- Affected by digital osteoarthritis meeting ACR diagnostic criteria with radiographic signs of osteoarthritis validated by a radiologist.
- For the control group :
- Rheumatology consultant at the Clermont-Ferrand University Hospital or hospitalized in this department for a non-arthritic, non-rheumatic pathology.
- Patients with spinal disc pathology (lumbago, radiculalgia due to disco-radicular conflict) or non-severe osteoporosis, i.e. with a densitometric T score between -2.5 and -3 DS.
Exclusion criteria
- For all topics :
- Refusal to participate
- Pregnant women, nursing mothers
- Subjects under guardianship or curatorship, deprived of liberty, or under court protection
- For the digital osteoarthritis group:
- \- Existence of diagnostic arguments for another inflammatory rheumatism (rheumatoid arthritis, spondylarthritis, psoriatic arthritis, lupus, gout, chondrocalcinosis...) or another arthrosic localization (gonarthrosis, coxarthrosis, discarthrosis) symptomatic at the time of inclusion or affecting daily activities.
- For the control group :
- Existence of chronic inflammatory rheumatism (rheumatoid arthritis, spondylitis, psoriatic arthritis, lupus, gout, chondrocalcinosis...)
- Existence of digital osteoarthritis
- Existence of another painful arthritic site (knee, hip, rachi) Existence of finger pain, whatever the etiology.
Where it is running
1 location listed.
- Chu Clermont Ferrand - Clermont-Ferrand, France