Identifying and Treating Depression in the Orthopaedic Trauma Population
Recruiting · NCT05976347 · Interventional (participants receive a specific treatment) · Lead sponsor: Wake Forest University Health Sciences
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this trial is to pilot a way for orthopaedic surgeons to safely screen for depression and provide treatment for depression with medication. The main questions it aims to answer are: 1. What are the outcomes of patients who screen positive for depressive symptoms and are prescribed either an Selective serotonin reuptake inhibitors (SSRI) or serotonin and norepinephrine reuptake inhibitors (SNRI). 2. What are the outcomes of patients who screen positive for depressive symptoms and choose not to pursue treatment with medication?
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Patients presenting to an Orthopaedic trauma clinic for the first time following operative extremity fracture or any pelvis fracture
- A score of greater than or equal to 5 on the Patient Health Questionnaire-9 (PHQ-9) at first post- operative visit
- Age 18 or older
- Speak English or Spanish
Exclusion criteria
- Currently taking medication to treat depression
- Contraindication/allergy to one of the study medications
- Bipolar disorder of psychotic disorder
- Endorse suicidal ideation
Where it is running
1 location listed across 1 US state.
- Wake Forest University Health Sciences - Winston-Salem, North Carolina, United States