Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
Recruiting · NCT05980793 · Interventional (participants receive a specific treatment) · Lead sponsor: Karolinska Institutet
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are: * Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise). Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.
Who can take part
Inclusion criteria
- Age ≥ 18 years.
- Chronic symptomatic osteoarthritis in the PIP-joint.
- Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV) (Kellgren \& Lawrence, 1957).
- Clinical signs of PIP-joint arthritis.
Exclusion criteria
- Inflammatory arthritis.
- Ongoing infection in the hand.
- Inability to co-operate with the follow-up protocol.
- Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment.
Where it is running
1 location listed.
- Department of Hand Surgery, Södersjukhuset - Stockholm, Sweden